n-acetylmannosamine Report issue

Small molecule Experimental
AACT DrugBank PubChem

Active Ingredient History

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N-Acetylmannosamine is a hexosamine monosaccharide. It is a neutral, stable naturally occurring compound. N-Acetylmannosamine is also known as N-Acetyl-D-mannosamine monohydrate,, N-Acetyl-D-mannosamine which can be abbreviated to ManNAc or, less commonly, NAM). ManNAc is the first committed biological precursor of N-acetylneuraminic acid. Sialic acids are the negatively charged, terminal monosaccharides of carbohydrate chains that are attached to glycoproteins and glycolipids (glycans).   Wikipedia

Chemistry

  • SMILES: CC(=O)N[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O
  • InChIKey: OVRNDRQMDRJTHS-UOLFYFMNSA-N
  • Mol. Mass: 221.21
  • ALogP: -3.08
  • ChEMBL Molecule:
    n-acetylmannosamine  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

mannac | n-acetylmannosamine | n-acetyl-mannosamine

Organizations (7)

Research & Development (7)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (2)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (2)


 

Kidney Diseases (Phase 1)

Musculoskeletal Diseases (Phase 2)

Overview

  • Highest Phase: Phase 2
  • # of Trials: 4
  • # of Trial Organizations: 7

Trials by Phase

Trial Phase Start Date Organizations Indications

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