lometrexol Report issue

Small molecule Experimental
AACT DrugBank MeSH PubChem

Active Ingredient History

NOW
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Chemistry

  • SMILES: Nc1nc2c(c(=O)[nH]1)C[C@@H](CCc1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1)CN2
  • InChIKey: ZUQBAQVRAURMCL-DOMZBBRYSA-N
  • Mol. Mass: 443.46
  • ALogP: 0.62
  • ChEMBL Molecule:
    lometrexol  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

5,10-ddtf | 5,10-dideaza-5,6,7,8-tetrahydrofolic acid | 5,10-dideazatetrahydrofolate | 5,10-dideazatetrahydrofolic acid | ddathf | lometrexol | lometrexol, (6r)-isomer | lometrexol, (6s)-isomer

Organizations (3)

Research & Development (3)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (3)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (3)


 

Drug-Related Side Effects and Adverse Reactions (Phase 1)

Lung Neoplasms (Phase 2)

Neoplasms (Phase 1)

Overview

  • Highest Phase: Phase 2
  • # of Trials: 2
  • # of Trial Organizations: 3

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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