API | tropifexor

tropifexor Report issue

Small molecule Experimental

AACT

Active Ingredient History

NOW

Chemistry

SMILES: O=C(O)c1cc(F)c2nc(N3[C@@H]4CC[C@H]3C[C@@H](OCc3c(-c5ccccc5OC(F)(F)F)noc3C3CC3)C4)sc2c1
InChIKey: VYLOOGHLKSNNEK-PIIMJCKOSA-N
Mol. Mass: 603.59
ALogP: 7.28 Partition coefficient
ChEMBL Molecule:
tropifexor

More Chemistry

Pharmacology

Mechanisms of Action:
- Bile acid receptor (Homo sapiens) ^UniProt
- Fragile X mental retardation syndrome-related protein 1 (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

ljn452

Organizations (2)

Research & Development (2)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (4)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (4)

Diarrhea (Phase 2)

Liver Cirrhosis, Biliary (Phase 2)

Liver Diseases (Phase 1)

Non-alcoholic Fatty Liver Disease (Phase 2)

Overview

Highest Phase: Phase 2
# of Trials: 8
# of Trial Organizations: 2

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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