API | Afabicin

Afabicin Report issue

Small molecule Experimental

AACT

Active Ingredient History

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Chemistry

SMILES: Cc1c(CN(C)C(=O)/C=C/c2cnc3c(c2)CCC(=O)N3COP(=O)(O)O)oc2ccccc12
InChIKey: HFYMDQMXVPJNTH-VQHVLOKHSA-N
Mol. Mass: 485.43
ALogP: 3.15 Partition coefficient
ChEMBL Molecule:
afabicin

More Chemistry

Pharmacology

Mechanisms of Action:
- Enoyl-ACP reductase (Plasmodium falciparum) ^UniProt
- Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI (Staphylococcus aureus (strain MRSA252)) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: Yes

debio 1450 | debio 1450 bes

Organizations (1)

Research & Development (1)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (3)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (3)

Bacterial Infections (Phase 2)

Bone Diseases, Infectious (Phase 2)

Healthy Volunteers (Phase 1)

Overview

Highest Phase: Phase 2
# of Trials: 7
# of Trial Organizations: 1

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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