fluoroestradiol (Cerianna) Report issue

Small molecule Imaging Approved FDA
AACT PubChem

Active Ingredient History

NOW
  • Now
Fluoroestradiol F-18, also known as [18F]16α-fluoroestradiol and sold under the brand name Cerianna, is a radioactive diagnostic agent indicated for use with positron emission tomography (PET) imaging. It is an analog of estrogen and is used to detect estrogen receptor-positive breast cancer lesions.   Wikipedia

Chemistry

  • SMILES: C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1C[C@@H](F)[C@@H]2O
  • InChIKey: KDLLNMRYZGUVMA-ZXXIGWHRSA-N
  • Mol. Mass: 290.38
  • ALogP: 3.56
  • ChEMBL Molecules:
    fluoroestradiol  
    fluoroestradiol f-18  
More Chemistry

Pharmacology

  • Mechanisms of Action:
  • Multi-specific: Missing data
  • Imaging: 18-fluorine
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Parenteral
  • Pro Drug: No

Alternative names

18f 16 alpha-fluoroestradiol | 18f fes | 18f fluoroestradiol | 6alpha-[18f]fluoro-17beta-estradiol | 6α-[18f]fluoro-17β-estradiol | f-18 16 alpha-fluoroestradiol | f-18 fes | fluorestradiol | fluoroestradiol | fluoroestradiol f-18

Organizations (24)

Research & Development (24)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (2)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (5)

Approved Indications (1)


 

Breast Neoplasms (approved 2020)

Experimental Indications - Clinical Trial Phases 1-4 (5)


 

Breast Neoplasms (Phase 4)

Carcinoma, Ovarian Epithelial (Phase 2)

Endometriosis (Phase 2)

Pulmonary Arterial Hypertension (Phase 1)

Uterine Neoplasms (Phase 2)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 28
  • # of Trial Organizations: 24

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

Report issue