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Small molecule Experimental

AACT ChEMBL MeSH PubChem

Active Ingredient History

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Chemistry

SMILES: Cc1cc(Nc2cc(N3CCN(C)CC3)nc(/C=C/c3ccccc3)n2)n[nH]1
InChIKey: BLQYVHBZHAISJM-CMDGGOBGSA-N
Mol. Mass: 375.48
ALogP: 3.17 Partition coefficient
ChEMBL Molecules:

enmd-2076

enmd-981693

More Chemistry

Pharmacology

Mechanisms of Action:
- Fibroblast growth factor receptor 3 (Homo sapiens) ^UniProt
- Macrophage colony-stimulating factor 1 receptor (Homo sapiens) ^UniProt
- Platelet-derived growth factor receptor alpha (Homo sapiens) ^UniProt
- Platelet-derived growth factor receptor beta (Homo sapiens) ^UniProt
- Aurora kinase A (Homo sapiens) ^UniProt
- Aurora kinase B (Homo sapiens) ^UniProt
- Mast/stem cell growth factor receptor Kit (Homo sapiens) ^UniProt
- Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens) ^UniProt
- Vascular endothelial growth factor receptor 2 (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

enmd2076 | enmd 2076 | enmd-2076 | enmd-981693 | mkc-1 | r-440 | ro-317453

Organizations (8)

Research & Development (8)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (18)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (18)

Breast Neoplasms (Phase 2)

Carcinoma, Hepatocellular (Phase 2)

Carcinoma, Non-Small-Cell Lung (Phase 1/Phase 2)

Colorectal Neoplasms (Phase 2)

Endometrial Neoplasms (Phase 2)

Fallopian Tube Neoplasms (Phase 2)

Hamartoma (Phase 2)

Hematologic Neoplasms (Phase 1)

Liver Neoplasms (Phase 2)

Multiple Myeloma (Phase 1)

Myelodysplastic Syndromes (Phase 1)

Neoplasm Metastasis (Phase 2)

Neoplasms (Phase 1/Phase 2)

Ovarian Neoplasms (Phase 2)

Pancreatic Neoplasms (Phase 2)

Primary Myelofibrosis (Phase 1)

Sarcoma (Phase 2)

Triple Negative Breast Neoplasms (Phase 2)

Overview

Highest Phase: Phase 2
# of Trials: 17
# of Trial Organizations: 8

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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