dimenhydrinate Report issue

Small molecule Approved FDA
AACT ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem repoDB

Active Ingredient History

NOW
  • Now
Dimenhydrinate, sold under the brand name Dramamine, among others, is an over-the-counter medication used to treat motion sickness and nausea. Dimenhydrinate is a theoclate salt composed of diphenhydramine and 8-chlorotheophylline in a 1:1 ratio.   Wikipedia

Chemistry

  • SMILES: CN1C2=C(N=C(Cl)N2)C(=O)N(C)C1=O.CN(C)CCOC(C3=CC=CC=C3)C4=CC=CC=C4
  • InChIKey: NFLLKCVHYJRNRH-UHFFFAOYSA-N
  • Mol. Mass: 469.964
  • ALogP: Missing data
  • ChEMBL Molecule:
    dimenhydrinate  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Oral, Parenteral
  • Pro Drug: No

Drug Pricing (per unit)

United States

$0.0119 - $8.5600
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Alternative names

8-chloro-1,3-dimethyl-3,7-dihydro-1h-purine-2,6-dione - 2-(diphenylmethoxy)-n,n-dimethylethanamine (1:1) | andramine | antemin | benzhydryl-beta-dimethylaminoethylether 8-chlorotheophylline | beta-dimethylaminoethyl benzhydryl ether 1,3-dimethyl-8-chloroxanthine | chloranautine | diamarin | dimenhidrinato | dimenhydrinate | dimenhydrinatum | diphenhydramine 8-chlorotheophyllinate | diphenhydramine 8-chlorotheophylline | diphenhydramine theoclate | diphenhydrinate | dramamine | dyme | menhydrinate | n,n-dimethyl-2-diphenylmethoxyethylamine 8-chlorotheophyllinate | (o-benzhydryl(dimethylamino)ethanol) 8-chlorotheophyllinate | o-benzhydryldimethylaminoethanol 8-chlorotheophyllinate | theohydramine | vertigo-vomex s

Organizations (21)

Research & Development (12)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (9)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (8)

Approved Indications (1)


 

Vomiting

Experimental Indications - Clinical Trial Phases 1-4 (8)


 

Cataract (Phase 3)

Gastroenteritis (Phase 4)

Nausea (Phase 4)

Pain (Phase 4)

Pain, Postoperative (Phase 4)

Postoperative Nausea and Vomiting (Phase 2)

Vertigo (Phase 4)

Vomiting (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 10
  • # of Trial Organizations: 12

Trials by Phase

Trial Phase Start Date Organizations Indications

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