Active Ingredient History
Cycloserine was discovered simultaneously in 1954 by Eli Lilly and Merck. The drug was approved for the treatment of active pulmonary and extrapulmonary tuberculosis and marketed under the name Seromycin (among the others). Cycloserine suppresses the synthesis of bacterial wall by inhibitin two enzymes: alanine racemase and d-alanine ligase. NCATS
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Tuberculosis (approved 1964)
Agoraphobia (Phase 2)
Alcohol Drinking (Phase 2/Phase 3)
Anxiety (Phase 2)
Anxiety Disorders (Phase 1)
Asperger Syndrome (Phase 3)
Autistic Disorder (Phase 3)
Bipolar Disorder (Phase 4)
Body Dysmorphic Disorders (Early Phase 1)
Brain Injuries, Traumatic (Phase 2)
Breast Neoplasms (Phase 3)
Cigarette Smoking (Phase 2)
Cocaine-Related Disorders (Phase 2)
Depression (Phase 2)
Depressive Disorder, Major (Phase 2)
Depressive Disorder, Treatment-Resistant (Phase 4)
Feeding and Eating Disorders (Phase 1/Phase 2)
Fibromyalgia (Phase 2)
Growth and Development (Phase 3)
Gulf War (Phase 2)
Harm Reduction (Phase 2)
HIV Infections (Phase 4)
Low Back Pain (Phase 3)
Motor Activity (Phase 2)
Obsessive-Compulsive Disorder (Phase 4)
Opioid-Related Disorders (Phase 2)
Pain (Phase 3)
Panic Disorder (Phase 3)
Phobia, Social (Phase 4)
Phobic Disorders (Phase 3)
Placebos (Phase 2)
Prostatitis (Phase 4)
Psychotic Disorders (Phase 4)
Pulmonary Disease, Chronic Obstructive (Early Phase 1)
Pyelonephritis (Phase 2)
Schizophrenia (Phase 4)
Schizophrenia, Paranoid (Phase 4)
Sleep Apnea Syndromes (Phase 1)
Smokers (Phase 2)
Smoking Cessation (Phase 3)
Spinal Cord Injuries (Phase 4)
Stress Disorders, Post-Traumatic (Phase 4)
Stroke (Phase 2)
Substance-Related Disorders (Phase 2)
Suicidal Ideation (Phase 2/Phase 3)
Suicide (Phase 2/Phase 3)
Suicide, Attempted (Phase 2/Phase 3)
Therapeutics (Phase 2)
Tobacco Use Disorder (Phase 1)
Tourette Syndrome (Early Phase 1)
Tuberculosis (Phase 3)
Tuberculosis, Multidrug-Resistant (Phase 4)
Tuberculosis, Pulmonary (Phase 3)
Urinary Tract Infections (Phase 2)
Trial | Phase | Start Date | Organizations | Indications |
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