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Small molecule Experimental

Active Ingredient History

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Chemistry

SMILES: Nc1nc2cc(-c3ccc4ncc(C(=O)N5CCOCC5)n4c3)ccc2o1
InChIKey: BLGWHBSBBJNKJO-UHFFFAOYSA-N
Mol. Mass: 363.38
ALogP: 2.2 Partition coefficient
ChEMBL Molecule:
serabelisib

More Chemistry

Pharmacology

Mechanisms of Action:
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens) ^UniProt
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

Organizations (3)

Research & Development (3)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (7)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (7)

Breast Neoplasms (Phase 1/Phase 2)

Colorectal Neoplasms (Phase 1/Phase 2)

Endometrial Neoplasms (Phase 1/Phase 2)

Head and Neck Neoplasms (Phase 1/Phase 2)

Lung Neoplasms (Phase 1/Phase 2)

Mutation (Phase 1)

Neoplasms (Phase 1)

Overview

Highest Phase: Phase 2
# of Trials: 2
# of Trial Organizations: 3

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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