Silibinin Report issue

Small molecule Experimental
AACT ChEMBL DrugBank MeSH PubChem

Active Ingredient History

NOW
  • Now
Chlordiazepoxide, trade name Librium among others, is a sedative and hypnotic medication of the benzodiazepine class; it is used to treat anxiety, insomnia and symptoms of withdrawal from alcohol and other drugs.   Wikipedia

Chemistry

  • SMILES: COc1cc(C2Oc3cc(C4Oc5cc(O)cc(O)c5C(=O)C4O)ccc3OC2CO)ccc1O
  • InChIKey: SEBFKMXJBCUCAI-UHFFFAOYSA-N
  • Mol. Mass: 482.44
  • ALogP: 2.36
  • ChEMBL Molecule:
    silibinin  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

2,3-dehydrosilybin | alepa-forte | ardeyhepan | cdp | cefasilymarin | durasilymarin | hepabesch | hepa-loges | hepa-merz sil | hepar-pasc | heparsyx | hepatos | heplant | lagosa | legalon forte | silibin | silibinin | silibrin | silybin | silybinin

Organizations (37)

Research & Development (37)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (21)

Approved Indications (1)


 

Liver Diseases

Experimental Indications - Clinical Trial Phases 1-4 (20)


 

Acute-On-Chronic Liver Failure (Phase 4)

Carcinoma, Hepatocellular (Phase 1)

Carcinoma, Non-Small-Cell Lung (Phase 2)

Depression (Phase 3)

Diabetic Nephropathies (Phase 2)

Healthy Volunteers (Phase 1)

Hepatitis C (Phase 2)

Hepatitis C, Chronic (Phase 2/Phase 3)

HIV (Phase 2)

Hypertension (Phase 4)

Inflammation ()

Ischemic Stroke (Phase 2)

Liver Cirrhosis (Phase 3)

Liver Failure (Phase 3)

Mushroom Poisoning (Phase 2/Phase 3)

Oxidative Stress (Phase 2)

Prostatic Neoplasms (Phase 2)

Proteinuria (Phase 2)

Smoking (Phase 1)

Work (Phase 3)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 25
  • # of Trial Organizations: 37

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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