Active Ingredient History
Darvadstrocel, sold under the brand name Alofisel, is a medication used to treat complex perianal fistulas in adults with non-active/mildly active luminal Crohn's disease when fistulas have shown an inadequate response to at least one conventional or biologic therapy. It contains mesenchymal stem cells from fat tissue of adult donors. Wikipedia
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Adipose Tissue (Phase 2)
Aging (Phase 1/Phase 2)
Alopecia (Phase 4)
Alzheimer Disease (Phase 1)
Amyotrophic Lateral Sclerosis (Phase 2)
Anemia, Aplastic (Phase 1/Phase 2)
Arthritis, Rheumatoid (Phase 1/Phase 2)
Autoimmune Diseases (Phase 1/Phase 2)
Autoimmune Diseases of the Nervous System (Phase 1/Phase 2)
Back Pain (Phase 1/Phase 2)
Cardiomyopathies (Phase 2)
Cartilage Diseases (Phase 1/Phase 2)
Cerebral Palsy (Phase 3)
Chronic Limb-Threatening Ischemia (Phase 2)
Cicatrix (Phase 1/Phase 2)
Colitis, Ulcerative (Phase 1/Phase 2)
Conjunctivitis (Early Phase 1)
Corneal Diseases (Phase 1/Phase 2)
Corneal Dystrophies, Hereditary (Phase 1/Phase 2)
Corneal Ulcer (Phase 1/Phase 2)
Coronavirus Infections (Phase 2)
COVID-19 (Phase 2/Phase 3)
Crohn Disease (Phase 4)
Cutis Laxa (Phase 1/Phase 2)
Cytokines (Phase 1)
Deficiency Diseases (Early Phase 1)
Delayed Graft Function (Phase 1)
Demyelinating Autoimmune Diseases, CNS (Phase 1/Phase 2)
Demyelinating Diseases (Phase 1/Phase 2)
Diabetes Mellitus (Phase 1)
Diabetes Mellitus, Type 1 (Phase 1)
Diabetes Mellitus, Type 2 (Phase 1)
Diabetic Foot (Phase 1/Phase 2)
Diabetic Nephropathies (Phase 1)
Drug-Related Side Effects and Adverse Reactions (Phase 1/Phase 2)
Dry Eye Syndromes (Early Phase 1)
Dystrophin (Phase 1)
Fractures, Bone (Phase 1/Phase 2)
Hair (Phase 3)
Healthy Aging (Phase 1)
Herpes Zoster (Phase 2)
Humans (Phase 2)
Immune System Diseases (Phase 1/Phase 2)
Inflammation (Phase 1/Phase 2)
Intervertebral Disc Degeneration (Phase 1)
Keloid (Phase 2)
Liver Cirrhosis (Phase 2)
Long Term Adverse Effects (Phase 1/Phase 2)
Low Back Pain (Phase 1)
Lymphedema (Phase 3)
Medicine, Chinese Traditional (Phase 1/Phase 2)
Mesenchymal Stem Cells (Phase 1/Phase 2)
Mouth (Phase 1/Phase 2)
Myositis, Inclusion Body (Phase 1)
Nervous System Diseases (Phase 1/Phase 2)
Osteoarthritis (Phase 2)
Osteoarthritis, Hip (Phase 2)
Osteoarthritis, Knee (Phase 2/Phase 3)
Paralysis (Phase 2)
Peripheral Arterial Disease (Early Phase 1)
Pharmacokinetics (Phase 1/Phase 2)
Pharmacological and Toxicological Phenomena (Phase 1/Phase 2)
Post-Concussion Syndrome (Phase 1)
Psoriasis (Phase 1/Phase 2)
Rectal Fistula (Phase 4)
Regenerative Medicine (Phase 1)
Renal Insufficiency (Phase 1)
Renal Insufficiency, Chronic (Phase 1)
Rotator Cuff Injuries (Phase 2)
Safety (Phase 2)
Scleroderma, Systemic (Phase 2)
Sexual Dysfunction, Physiological (Phase 2)
Skin (Phase 1/Phase 2)
Spinal Cord Injuries (Phase 2)
Stroke (Phase 2/Phase 3)
Tennis Elbow (Phase 2)
Ulcer (Phase 1/Phase 2)
Urethral Stricture (Phase 2)
Urinary Incontinence (Phase 1/Phase 2)
Urinary Incontinence, Stress (Phase 1/Phase 2)
Xerostomia (Phase 1/Phase 2)
Trial | Phase | Start Date | Organizations | Indications |
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