API | islatravir

islatravir Report issue

Small molecule Experimental

AACT PubChem

Active Ingredient History

NOW

Islatravir is an investigational drug for the treatment of HIV infection. It is classified as a nucleoside reverse transcriptase translocation inhibitor (NRTTI). Merck is developing a subdermal drug-eluting implant to administer islatravir. ^Wikipedia

Chemistry

SMILES: C#C[C@]1(CO)O[C@@H](n2cnc3c(N)nc(F)nc32)C[C@@H]1O
InChIKey: IKKXOSBHLYMWAE-QRPMWFLTSA-N
Mol. Mass: 293.26
ALogP: -0.81 Partition coefficient
ChEMBL Molecule:
islatravir

More Chemistry

Pharmacology

Mechanisms of Action:
- Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) ^UniProt
- Reverse transcriptase (Human immunodeficiency virus 2) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

mk-8591

Organizations (2)

Research & Development (2)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (3)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (3)

HIV (Phase 2)

HIV-1 (Phase 3)

HIV Infections (Phase 3)

Overview

Highest Phase: Phase 3
# of Trials: 22
# of Trial Organizations: 2

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

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