API | azd-8186

azd-8186 Report issue

Small molecule Experimental

AACT ChEMBL PubChem

Active Ingredient History

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Chemistry

SMILES: C[C@@H](Nc1cc(F)cc(F)c1)c1cc(C(=O)N(C)C)cc2c(=O)cc(N3CCOCC3)oc12
InChIKey: LMJFJIDLEAWOQJ-CQSZACIVSA-N
Mol. Mass: 457.48
ALogP: 3.78 Partition coefficient
ChEMBL Molecules:

azd-8186

azd-8186

More Chemistry

Pharmacology

Mechanisms of Action:
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens) ^UniProt
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

azd8186 | azd-8186

Organizations (2)

Research & Development (2)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (3)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (3)

Breast Neoplasms (Phase 1)

Carcinoma, Non-Small-Cell Lung (Phase 1)

Prostatic Neoplasms, Castration-Resistant (Phase 1)

Overview

Highest Phase: Phase 1
# of Trials: 1
# of Trial Organizations: 2

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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