Active Ingredient History

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Lypressin is synthetic analog of porcine antidiuretic hormone vasopressin. Itis a cyclic nonapeptide that differs from Arg-vasopressin by one amino acid, containing Lys at residue 8 instead of Arg. Lypressin-containing nasal spray was used to treat diabetes insipidus, but its marketing by Sandoz (Novartis) was discontinued.   NCATS

  • SMILES: NCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)NCC(N)=O
  • InChIKey: BJFIDCADFRDPIO-DZCXQCEKSA-N
  • Mol. Mass: 1056.24
  • ALogP: Missing data
  • ChEMBL Molecule:
More Chemistry
diapid | l-8 | lypressin | lysine pitressin | lysine vasopressin | lysipressin | lysopressin | lysylvasopressin | syntopressin

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