Active Ingredient History
Moxifloxacin is a synthetic antibacterial agent developed by Bayer AG (initially called BAY 12-8039) for oral and intravenous administration. Moxifloxacin, a fluoroquinolone, is available as the monohydrochloride salt of 1-cyclopropyl-7-[(S,S)-2,8diazabicyclo[4.3.0]non-8-yl]-6-fluoro-8-methoxy-1,4-dihydro-4-oxo-3 quinoline carboxylic acid. Moxifloxacin is marketed worldwide (as the hydrochloride) under the brand names Avelox, Avalox, and Avalon for oral treatment. In most countries, the drug is also available in the parenteral form for intravenous infusion. Moxifloxacin is also sold in an ophthalmic solution (eye drops) under the brand names Vigamox, and Moxeza for the treatment of conjunctivitis (pink eye). Its antibacterial spectrum includes enteric Gram-(−) rods (Escherichia coli, Proteus species, Klebsiella species), Haemophilus influenzae, atypical bacteria (Mycoplasma, Chlamydia, Legionella), and Streptococcus pneumoniae, and anaerobic bacteria. It differs from earlier antibacterials of the fluoroquinolone class such as levofloxacin and ciprofloxacin in having greater activity against Gram-positive bacteria and anaerobes. NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Abdominal Abscess (Phase 3)
Abscess (Phase 4)
Acanthamoeba Keratitis (Phase 3)
Acne Vulgaris (Phase 1)
Acute Coronary Syndrome (Phase 1)
Aggressive Periodontitis (Phase 4)
Alzheimer Disease (Phase 1)
Amyotrophic Lateral Sclerosis (Phase 1)
Anemia (Phase 1)
Anti-Bacterial Agents (Phase 2)
Arrhythmias, Cardiac (Phase 4)
Arthritis, Rheumatoid (Phase 1)
Asthma (Phase 4)
Astrocytoma (Phase 1)
Autoimmune Diseases (Phase 1)
Bacteremia (Phase 3)
Bacterial Infections (Phase 4)
Blepharitis (Phase 3)
Blood Glucose (Phase 1)
Body Weight (Phase 4)
Brain Injuries (Phase 2)
Brain Neoplasms (Phase 1)
Breast Neoplasms (Phase 3)
Carcinoma, Renal Cell (Phase 1)
Cardiotoxicity (Phase 1)
Cardiovascular Abnormalities (Phase 1)
Cardiovascular Diseases (Phase 1)
Cataract (Phase 4)
Cataract Extraction (Phase 4)
Cellulitis (Phase 3)
Cholangitis (Phase 2)
Cholecystitis, Acute (Phase 3)
Chronic Periodontitis (Phase 4)
Communicable Diseases (Phase 3)
Community-Acquired Infections (Phase 4)
Conjunctivitis (Phase 4)
Constipation (Phase 1)
Contraception (Phase 1)
Corneal Diseases (Phase 4)
Corneal Edema (Phase 4)
Corneal Injuries (Phase 4)
Corneal Transplantation (Phase 4)
Corneal Ulcer (Phase 4)
Coronary Artery Disease (Phase 1)
Cough (Phase 1)
COVID-19 (Phase 4)
Cystic Fibrosis (Phase 1)
Cysts (Phase 4)
Diabetes Mellitus (Phase 1)
Diabetes Mellitus, Type 2 (Phase 1)
Diabetic Foot (Phase 3)
Diet Therapy (Early Phase 1)
Disease Progression (Phase 2)
Drug Resistance, Bacterial (Phase 4)
Drug Resistance, Microbial (Phase 4)
Drugs, Generic (Phase 1)
Drugs, Investigational (Phase 1)
Dyslipidemias (Phase 1)
Dyspepsia (Phase 1)
Edema (Phase 4)
Electrocardiography (Phase 1)
Endocarditis (Phase 4)
Endometriosis (Phase 1)
Endophthalmitis (Phase 4)
Epilepsy (Phase 1)
Erectile Dysfunction (Phase 1)
Extensively Drug-Resistant Tuberculosis (Phase 2/Phase 3)
Eye Infections (Phase 4)
Eye Infections, Bacterial (Phase 4)
Fibromyalgia (Phase 1)
Gastric Bypass (Phase 4)
Gastritis (Phase 3)
Gastrointestinal Microbiome (Phase 4)
General Surgery (Phase 4)
Gestational Trophoblastic Disease (Phase 3)
Glioblastoma (Phase 1)
Gonorrhea (Phase 1)
Gout (Early Phase 1)
Graft vs Host Disease (Phase 2)
Healthy Volunteers (Phase 4)
Heart (Phase 4)
Heart Diseases (Phase 1)
Heart Failure (Phase 1)
Helicobacter Infections (Phase 4)
Helicobacter pylori (Phase 3)
Hepatitis C (Phase 1)
Herpes Simplex (Phase 1)
HIV (Phase 2)
HIV Infections (Phase 4)
Hodgkin Disease (Phase 3)
Hot Flashes (Phase 1)
Hypertension (Phase 1)
Hyperuricemia (Early Phase 1)
Hypoglycemia (Phase 1)
Hypotension (Phase 1)
IgG Deficiency (Phase 4)
Infant, Premature (Phase 1)
Infections (Phase 4)
Inflammation (Phase 4)
Influenza, Human (Phase 1)
Intraabdominal Infections (Phase 4)
Keratitis (Phase 4)
Leukemia (Phase 3)
Lice Infestations (Phase 1)
Liver Abscess (Phase 4)
Lung Abscess (Phase 3)
Lung Diseases (Phase 3)
Lupus Erythematosus, Systemic (Phase 1)
Lymphoma (Phase 3)
Lymphoma, Non-Hodgkin (Phase 3)
Macular Edema (Phase 4)
Malaria, Falciparum (Phase 1)
Malaria, Vivax (Phase 1)
Maxillary Sinusitis (Phase 4)
Mineralocorticoid Receptor Antagonists (Phase 1)
Moxifloxacin (Phase 2)
Multiple Myeloma (Phase 3)
Muscle Spasticity (Phase 2)
Muscular Dystrophy, Duchenne (Phase 1)
Mycobacterium tuberculosis (Phase 1)
Myelodysplastic Syndromes (Phase 3)
Myeloproliferative Disorders (Phase 3)
Neoplasms (Phase 2)
Neuroblastoma (Phase 3)
Non-alcoholic Fatty Liver Disease (Phase 1)
Obesity (Phase 1)
Osteomyelitis (Phase 2)
Otitis Externa (Phase 3)
Otitis Media (Phase 3)
Ovarian Neoplasms (Phase 3)
Pain (Phase 4)
Pain, Postoperative (Phase 1)
Parkinson Disease (Phase 2)
Pelvic Inflammatory Disease (Phase 4)
Periodontitis (Phase 4)
Pharmacokinetics (Phase 2)
Phenylketonurias (Phase 1)
Pneumonia ()
Pneumonia, Aspiration (Phase 3)
Pneumonia, Bacterial (Phase 3)
Polycythemia Vera (Phase 1)
Postoperative Complications (Phase 4)
Postpartum Hemorrhage (Phase 1)
Prosthesis-Related Infections (Phase 3)
Psychotic Disorders (Phase 1)
Pulmonary Arterial Hypertension (Phase 1)
Pulmonary Disease, Chronic Obstructive (Phase 4)
Pyelonephritis (Phase 4)
Respiratory Tract Infections (Phase 1)
Restless Legs Syndrome (Phase 1)
Retinal Diseases (Phase 4)
Safety (Phase 1)
Schizophrenia (Phase 1)
Sepsis (Phase 3)
Shock, Septic (Phase 3)
Sinusitis (Phase 4)
Smoking Cessation (Phase 1)
Testicular Neoplasms (Phase 3)
Therapeutic Equivalency (Phase 1)
Traumatology (Phase 2)
Triple Negative Breast Neoplasms (Phase 3)
Tuberculosis (Phase 4)
Tuberculosis, Meningeal (Phase 3)
Tuberculosis, Multidrug-Resistant (Phase 3)
Tuberculosis, Pulmonary (Phase 3)
Ulcer (Phase 3)
Urinary Bladder, Overactive (Phase 1)
Vasomotor System (Phase 1)
Vision, Ocular (Phase 4)
Vitreous Body (Phase 4)
Volunteers (Phase 1)
Wound Infection (Phase 3)
Trial | Phase | Start Date | Organizations | Indications |
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