Organization | Jazz Pharmaceuticals

Jazz Pharmaceuticals Report issue

Contributed to NME For profit Phase 1 Phase 2 Phase 3 Phase 4

Founded: Dublin Ireland (2003)

Organization Overview

First Clinical Trial

2003

NCT00003966

First Marketed Drug

2003

sodium oxybate (xyrem)

First NDA Approval

2019

solriamfetol (Sunosi)

Last Known Activity

2024

Timeline

NOW

Now

Mergers & Acquisitions

Historical Acquisition Tree

Alternative names

Jazz | JAZZ | Jazz Pharamceuticals | Jazz Pharmaceuticals | Jazz Pharmaceuticals, Inc | Jazz Pharmaceuticals, Inc. | Jazz Pharmaceuticals Ireland Limited | JAZZ PHARMACEUTICALS IRELAND LIMITED | JAZZ PHARMS | JAZZ PHARMS III | JAZZ PHARMS INC

Active Ingredients

Marketed Drugs (14)

Key: Jazz Pharmaceuticals (9) Acquired (5)

atoltivimab (Inmazeb) (2020)

calcium (2020)

clozapine (clozaril) (2004)

cytarabine (cytosar-u) (2017)

daunorubicin (cerubidine) (2017)

defibrotide (defitelio) (2016)

erwinia asparaginase (Erwinaze) (2011)

fluvoxamine (luvox) (2008)

lurbinectedin (Zepzelca) (2020 NDA)

maftivimab (Inmazeb) (2020)

odesivimab (Inmazeb) (2020)

siltuximab (sylvant) (2014)

sodium oxybate (xyrem) (2002)

solriamfetol (Sunosi) (2019 NDA)

Drugs in Phase 4 Trials (9)

Key: Jazz Pharmaceuticals (3) Acquired (6)

cannabidiol (Epidiolex) (10 trials)

clozapine (clozaril) (1 trial)

lidocaine (xylocaine) (1 trial)

modafinil (provigil) (2 trials)

sodium oxybate (xyrem) (24 trials)

solriamfetol (Sunosi) (13 trials)

tetracaine (pontocaine) (1 trial)

tetrahydrocannabinol (44 trials)

zolpidem (ambien) (1 trial)

Drugs in Phase 3 Trials (16)

Key: Jazz Pharmaceuticals (8) Acquired (8)

acetaminophen (tylenol) (1 trial)

atezolizumab (Tecentriq) (1 trial)

cannabis (2 trials)

carboplatin (paraplatin) (1 trial)

cytarabine (cytosar-u) (33 trials)

daunorubicin (cerubidine) (24 trials)

defibrotide (defitelio) (10 trials)

dronabinol (marinol) (3 trials)

erwinia asparaginase (Erwinaze) (9 trials)

etoposide (vepesid) (1 trial)

glsi-100 (1 trial)

jzp150 (2 trials)

lurbinectedin (Zepzelca) (10 trials)

midazolam (versed) (1 trial)

siltuximab (sylvant) (4 trials)

sodium chloride (1 trial)

Drugs in Phase 2 Trials (49)

Key: Jazz Pharmaceuticals (37) Acquired (12)

aldesleukin (Proleukin) (1 trial)

allogeneic cd34+ cells (1 trial)

avelumab (bavencio) (1 trial)

betaine (1 trial)

busulfan (Myleran) (1 trial)

cladribine (leustatin) (1 trial)

clonazepam (klonopin) (1 trial)

cx-8998 (3 trials)

cyclophosphamide (cytoxan) (1 trial)

dinutuximab (unituxin) (1 trial)

docetaxel (taxotere) (2 trials)

doxorubicin (Doxil) (2 trials)

enasidenib (idhifa) (2 trials)

Filgrastim (neupogen) (1 trial)

floxuridine (fudr) (1 trial)

fludarabine (fludara) (3 trials)

glasdegib (Daurismo) (1 trial)

hydrocortisone (solu-cortef) (1 trial)

idarubicin (idamycin) (1 trial)

ipilimumab (yervoy) (1 trial)

irinotecan (Camptosar) (1 trial)

jzp541 (1 trial)

melphalan (alkeran) (1 trial)

mercaptopurine (purinethol) (1 trial)

methotrexate (1 trial)

midostaurin (rydapt) (2 trials)

mitoxantrone (novantrone) (1 trial)

naltrexone (revia) (1 trial)

nivolumab (opdivo) (1 trial)

ofatumumab (arzerra) (1 trial)

paclitaxel (taxol) (2 trials)

pegaspargase (oncaspar) (1 trial)

pegcrisantaspase (1 trial)

prednisone (meticorten) (1 trial)

ramucirumab (cyramza) (1 trial)

rituximab (rituxan) (1 trial)

ruxolitinib (jakafi) (1 trial)

samarium-153 lexidronam (quadramet) (2 trials)

sodium bicarbonate (1 trial)

sodium phosphate (1 trial)

spartalizumab (1 trial)

Suvecaltamide (2 trials)

tamoxifen (nolvadex) (1 trial)

temozolomide (temodar) (2 trials)

tioguanine (Lanvis) (1 trial)

vincristine (oncovin) (1 trial)

zoledronic acid (zometa) (1 trial)

Drugs in Phase 1 Trials (25)

Key: Jazz Pharmaceuticals (9) Acquired (16)

177lu-cyt-500 (1 trial)

bevacizumab (avastin) (1 trial)

bicalutamide (casodex) (1 trial)

chlorphenesin (maolate) (1 trial)

fluconazole (diflucan) (1 trial)

fluorothymidine (1 trial)

gemtuzumab ozogamicin (mylotarg) (3 trials)

gilteritinib (1 trial)

goserelin (zoladex) (1 trial)

human serum albumin/interferon alpha2b fusion protein (1 trial)

hydroxychloroquine (plaquenil) (1 trial)

imgn632 (1 trial)

jzp441 (2 trials)

jzp815 (1 trial)

ketoconazole (nizoral) (1 trial)

mibefradil (Posicor) (3 trials)

moxifloxacin (avelox) (1 trial)

mpeg-r-crisantaspase (1 trial)

omeprazole (prilosec) (1 trial)

pembrolizumab (keytruda) (1 trial)

pentobarbital (nembutal) (1 trial)

rifampin (1 trial)

sm-153 (1 trial)

triazolam (halcion) (1 trial)

venetoclax (venclexta) (2 trials)

Indications

Experimental Indications (Clinical Trials, Phases 1-4)

Acute Lung Injury (Phase 1)

Adenocarcinoma (Phase 2)

Anemia, Refractory, with Excess of Blasts (Phase 2)

Anxiety Disorders (Phase 3)

Apnea (Phase 4)

Binge-Eating Disorder (Phase 4)

Bulimia (Phase 4)

Cataplexy (Phase 3)

Disease (Phase 3)

Disorders of Excessive Somnolence (Phase 3)

Epilepsy (Phase 2)

Essential Tremor (Phase 2)

Fatigue (Phase 4)

Fatigue Syndrome, Chronic (Phase 4)

Feeding and Eating Disorders (Phase 4)

Fibromyalgia (Phase 3)

Graft vs Host Disease (Phase 2)

Hematologic Diseases (Phase 2)

Hemiplegia (Phase 2)

Hepatic Veno-Occlusive Disease (Phase 3)

Hypersensitivity (Phase 2)

Idiopathic Hypersomnia (Phase 3)

Leukemia (Phase 3)

Leukemia, Lymphoid (Phase 3)

Leukemia, Myeloid (Phase 3)

Leukemia, Myeloid, Acute (Phase 3)

Lymphoma (Phase 2)

Lymphoma, Non-Hodgkin (Phase 2)

Mental Disorders (Phase 4)

Myelodysplastic Syndromes (Phase 2)

Myeloproliferative Disorders (Phase 2)

Myofascial Pain Syndromes (Phase 3)

Narcolepsy (Phase 3)

Neoplasm Metastasis (Phase 2)

Neoplasms (Phase 2)

Neurotoxicity Syndromes (Phase 2)

Pancreatic Neoplasms (Phase 2)

Parkinson Disease (Phase 2)

Philadelphia Chromosome (Phase 1)

Polycythemia (Phase 2)

Polycythemia Vera (Phase 2)

Precursor Cell Lymphoblastic Leukemia-Lymphoma (Phase 3)

Preleukemia (Phase 2)

REM Sleep Behavior Disorder (Phase 4)

Respiratory Aspiration (Phase 4)

Respiratory Distress Syndrome (Phase 1)

Respiratory Distress Syndrome, Newborn (Phase 1)

Schizophrenia (Phase 2)

Seizures (Phase 2)

Sleep Apnea, Obstructive (Phase 4)

Sleep Apnea Syndromes (Phase 4)

Sleepiness (Phase 3)

Sleep Initiation and Maintenance Disorders (Phase 2)

Syndrome (Phase 4)

Thrombocythemia, Essential (Phase 2)

Thrombocytosis (Phase 2)

Tremor (Phase 2)

Overview

Highest Phase: Phase 4
# of Trials: 190
# of Trial APIs: 99