Organization Overview
Historical Acquisition Tree
Alternative names
chlorzoxazone (parafon forte dsc) (1958 NDA)
cyclobenzaprine (flexeril) (1977 NDA)
daratumumab (darzalex) (2015 NDA)
esketamine (spravato) (2019 NDA)
ketoconazole (nizoral) (1981 NDA)
ponesimod (Ponvory) (2021)
abiraterone (zytiga) (31 trials)
acetaminophen (tylenol) (13 trials)
acetylsalicylic acid (aspirin) (7 trials)
almotriptan (axert) (4 trials)
apalutamide (erleada) (34 trials)
aripiprazole (abilify) (4 trials)
bictegravir (Biktarvy) (5 trials)
canagliflozin (invokana) (10 trials)
celecoxib (celebrex) (1 trial)
clopidogrel (plavix) (4 trials)
cobicistat (stribild) (20 trials)
darunavir (prezista) (32 trials)
dolutegravir (tivicay) (10 trials)
elvitegravir (vitekta) (2 trials)
esketamine (spravato) (4 trials)
estradiol (progynon depot) (3 trials)
etravirine (intelence) (8 trials)
fentanyl (Innovar) (18 trials)
gabapentin (neurontin) (1 trial)
galantamine (reminyl) (8 trials)
golimumab (simponi) (11 trials)
guselkumab (tremfya) (28 trials)
haloperidol (haldol) (3 trials)
hydromorphone (diladid) (6 trials)
ibrutinib (imbruvica) (37 trials)
infliximab (remicade) (5 trials)
itraconazole (sporanox) (9 trials)
lamivudine (epivir) (6 trials)
lansoprazole (prevacid) (2 trials)
methylphenidate (ritalin) (8 trials)
miconazole (monistat) (1 trial)
norelgestromin (Evra) (3 trials)
olanzapine (zyprexa) (11 trials)
omeprazole (prilosec) (2 trials)
oxybutynin (ditropan) (1 trial)
paliperidone (invega) (28 trials)
perphenazine (trilafon) (2 trials)
prasugrel (effient) (2 trials)
prednisone (meticorten) (32 trials)
propranolol (inderal) (2 trials)
quetiapine (seroquel) (7 trials)
rabeprazole (pariet) (10 trials)
raltegravir (isentress) (2 trials)
ribavirin (virazole) (19 trials)
ritonavir (Norvir) (17 trials)
rivaroxaban (xarelto) (22 trials)
simeprevir (olysio) (31 trials)
sitagliptin (januvia) (2 trials)
sofosbuvir (sovaldi) (11 trials)
tapentadol (nucynta) (5 trials)
tenofovir (viread) (26 trials)
tenofovir alafenamide (genvoya) (17 trials)
ticagrelor (brilinta) (3 trials)
topiramate (topamax) (10 trials)
ustekinumab (stelara) (25 trials)
ad26.zebov (Zabdeno) (14 trials)
adalimumab (humira) (4 trials)
amivantamab-vmjw (Rybrevant) (11 trials)
atazanavir (reyataz) (4 trials)
bedaquiline (sirturo) (11 trials)
bortezomib (velcade) (38 trials)
bupropion (wellbutrin) (1 trial)
cabotegravir (Vocabria) (9 trials)
carboplatin (paraplatin) (8 trials)
carfilzomib (kyprolis) (10 trials)
clarithromycin (biaxin) (2 trials)
cyclophosphamide (cytoxan) (16 trials)
cytarabine (cytosar-u) (2 trials)
daratumumab (darzalex) (78 trials)
daunorubicin (cerubidine) (1 trial)
decitabine (dacogen) (7 trials)
docetaxel (taxotere) (4 trials)
enoxaparin (lovenox) (1 trial)
enzalutamide (xtandi) (2 trials)
epirubicin (ellence) (1 trial)
ethambutol (myambutol) (4 trials)
etoposide (vepesid) (6 trials)
Filgrastim (neupogen) (2 trials)
fludarabine (fludara) (2 trials)
fluindione (previscan) (1 trial)
fluorouracil (efudex) (1 trial)
gemcitabine (gemzar) (7 trials)
idarubicin (idamycin) (1 trial)
inactivated influenza vaccine (3 trials)
interferon alpha-2b (Intron-A) (14 trials)
janssen SARS-CoV2 vaccine (15 trials)
lenalidomide (revlimid) (31 trials)
leuprolide (lupron) (10 trials)
lopinavir (Kaletra) (4 trials)
melphalan (alkeran) (7 trials)
mosaic gp140 hiv bivalent vaccine (1 trial)
mva-bn-filo (Mvabea) (14 trials)
osimertinib (tagrisso) (1 trial)
phenprocoumon (liquamar) (1 trial)
pomalidomide (pomalyst) (12 trials)
remifentanil (ultiva) (1 trial)
rifabutin (mycobutin) (1 trial)
rituximab (rituxan) (14 trials)
sertraline (zoloft) (4 trials)
teclistamab (Tecvayli) (10 trials)
telaprevir (incivek) (7 trials)
thalidomide (Thalomid) (4 trials)
abemaciclib (verzenio) (1 trial)
allogeneic adipose derived mesenchymal stem cell (1 trial)
aluminum hydroxide (Gaviscon) (1 trial)
aminoglutethimide (cytadren) (1 trial)
aminosalicylic acid (Paser) (1 trial)
autologous hematopoietic stem cells (1 trial)
azacitidine (vidaza) (6 trials)
bendamustine (treanda) (1 trial)
bevacizumab (avastin) (3 trials)
biotinylated red blood cells (1 trial)
cabazitaxel (jevtana kit) (2 trials)
cobimetinib (cotellic) (1 trial)
cycloserine (seromycin) (1 trial)
cyclosporine (sandimmune) (2 trials)
daclatasvir (daklinza) (2 trials)
dasatinib (sprycel) (2 trials)
degarelix acetate (firmagon) (4 trials)
dupilumab (dupixent) (1 trial)
entecavir (baraclude) (8 trials)
erdafitinib (Balversa) (6 trials)
escitalopram (lexapro) (1 trial)
ethionamide (trecator) (1 trial)
everolimus (zortress) (1 trial)
Ga 68 PSMA-11 (Illuccix) (1 trial)
hpv 16/18 vaccine (Cervarix) (1 trial)
human choriogonadotropin alfa (hCG) (1 trial)
Inactivated polio virus - Enhanced (IPOL) (2 trials)
indomethacin (indocin) (2 trials)
interferon alpha-2a (roferon-a) (3 trials)
irinotecan (Camptosar) (2 trials)
ketoconazole (nizoral) (1 trial)
ledipasvir (Harvoni) (1 trial)
mebendazole (vermox) (1 trial)
Meningococcal (Groups A, C, Y, W) Conjugate Vaccine (MenQuadfi) (2 trials)
metformin (glucophage) (4 trials)
mitomycin (mutamycin) (1 trial)
monoaluminum phosphate (1 trial)
moxifloxacin (avelox) (4 trials)
nesiritide (natrecor) (1 trial)
obinutuzumab (gazyva) (1 trial)
oseltamivir (tamiflu) (2 trials)
pneumococcal 13-valent conjugate vaccine (prevnar 13) (1 trial)
polio, inactivated poliovirus vaccine (Salk Vaccine) (2 trials)
prednisolone (hydeltra) (1 trial)
pyrazinamide (Aldinamide) (3 trials)
recombinant human gdf-5 (1 trial)
sargramostim (leukine) (2 trials)
siltuximab (sylvant) (4 trials)
streptomycin (kabikinase) (1 trial)
tacrolimus (prograf) (1 trial)
Talquetamab (Talvey) (8 trials)
temozolomide (temodar) (1 trial)
trabectedin (yondelis) (4 trials)
trastuzumab (herceptin) (1 trial)
venetoclax (venclexta) (5 trials)
venlafaxine (effexor) (1 trial)
atorvastatin (lipitor) (1 trial)
belimumab (benlysta) (1 trial)
candida albicans allergen (Candin) (2 trials)
carbamazepine (tegretol) (2 trials)
coagulation factor viia (recombinant) (NovoSevenRT) (1 trial)
dabigatran (pradaxa) (1 trial)
drospirenone (Yasmin) (1 trial)
fluticasone (cutivate) (2 trials)
human factor ix complex (prothrombin complex concentrate) (Bebulin) (3 trials)
hyaluronidase (bovine) (Wydase) (1 trial)
hydrochlorothiazide (esidrix) (2 trials)
loperamide (imodium) (1 trial)
mosaic gp140 env trimers (1 trial)
nicotine (nicorette) (3 trials)
petrolatum, white (Vaseline) (1 trial)
phenytoin (mesantoin) (1 trial)
ponesimod (Ponvory) (2 trials)
risankizumab (Skyrizi) (1 trial)
rosuvastatin (crestor) (2 trials)
salmonella typhi vaccine (1 trial)
scopolamine (transderm scop) (1 trial)
secukinumab (cosentyx) (1 trial)
suvorexant (belsomra) (1 trial)
tofacitinib (xeljanz) (2 trials)
Acne Vulgaris (Phase 1)
Acquired Immunodeficiency Syndrome (Phase 4)
Acute Disease (Phase 4)
Adenocarcinoma (Phase 4)
Adenocarcinoma of Lung (Phase 2)
Aggression (Phase 4)
Alcoholism (Phase 4)
Alzheimer Disease (Phase 4)
Amyloidosis (Phase 2)
Anemia (Phase 4)
Anemia, Neonatal (Phase 2)
Anemia, Sickle Cell (Phase 2)
Anorexia (Phase 4)
Anorexia Nervosa (Phase 4)
Anxiety Disorders (Phase 4)
Arteritis (Phase 2)
Arthritis (Phase 4)
Arthritis, Psoriatic (Phase 3)
Arthritis, Rheumatoid (Phase 4)
Asperger Syndrome (Phase 3)
Aspergillosis (Phase 3)
Asthma (Phase 3)
Astrocytoma (Phase 2)
Atrial Fibrillation (Phase 4)
Autism Spectrum Disorder (Phase 3)
Autistic Disorder (Phase 3)
Autoimmune Diseases (Phase 3)
Back Pain (Phase 4)
Behcet Syndrome (Phase 3)
Bipolar Disorder (Phase 4)
Blastomycosis (Phase 3)
Borderline Personality Disorder (Phase 4)
Brain Diseases (Phase 2)
Breakthrough Pain (Phase 4)
Breast Neoplasms (Phase 3)
Cancer Pain (Phase 4)
Candidiasis (Phase 4)
Carcinoma (Phase 2)
Carcinoma, Hepatocellular (Phase 2)
Carcinoma, Non-Small-Cell Lung (Phase 3)
Carcinoma, Ovarian Epithelial (Phase 2)
Cardiovascular Diseases (Phase 4)
Central Nervous System Diseases (Phase 2)
Chronic Pain (Phase 4)
Cocaine-Related Disorders (Phase 2)
Cognition Disorders (Phase 1)
Cognitive Dysfunction (Phase 2)
Coinfection (Phase 4)
Colitis (Phase 3)
Colitis, Ulcerative (Phase 3)
Colonic Diseases (Phase 2)
Colorectal Neoplasms (Phase 2)
Communicable Diseases (Phase 4)
Complex Regional Pain Syndromes (Phase 3)
Compulsive Personality Disorder (Phase 4)
Conduct Disorder (Phase 3)
Coronary Artery Disease (Phase 4)
Coronary Disease (Phase 4)
Coronavirus Infections (Phase 3)
Critical Illness (Phase 2)
Crohn Disease (Phase 4)
Crush Injuries (Phase 1)
Cryptococcosis (Phase 3)
Cryptosporidiosis (Phase 1)
Cytomegalovirus Infections (Phase 4)
Delusions (Phase 3)
Dementia (Phase 4)
Dementia, Vascular (Phase 3)
Dengue (Phase 2)
Depression (Phase 4)
Depressive Disorder (Phase 4)
Depressive Disorder, Major (Phase 3)
Depressive Disorder, Treatment-Resistant (Phase 4)
Dermatitis (Phase 2)
Dermatitis, Atopic (Phase 2)
Dermatomyositis (Phase 3)
Developmental Disabilities (Phase 3)
Diabetes Mellitus (Phase 4)
Diabetes Mellitus, Type 1 (Phase 3)
Diabetes Mellitus, Type 2 (Phase 4)
Diabetic Neuropathies (Phase 4)
Diarrhea (Phase 1)
Disease (Phase 4)
Disease Progression (Phase 3)
Ear Diseases (Phase 2)
Eczema (Phase 2)
Embolism (Phase 4)
Emergencies (Phase 4)
Epilepsy (Phase 4)
Epilepsy, Rolandic (Phase 4)
Epstein-Barr Virus Infections (Phase 4)
Esophagitis (Phase 4)
Esophagitis, Peptic (Phase 4)
Febrile Neutropenia (Phase 3)
Fibrosis (Phase 3)
Frailty (Phase 2)
Gastroesophageal Reflux (Phase 4)
Gastroparesis (Phase 3)
Giant Cell Arteritis (Phase 2)
Glioblastoma (Phase 2)
Glioma (Phase 2)
Gliosarcoma (Phase 2)
Graft vs Host Disease (Phase 4)
Hallucinations (Phase 3)
Headache (Phase 4)
Heart Arrest (Phase 3)
Heartburn (Phase 3)
Heart Failure (Phase 4)
Heart Failure, Systolic (Phase 4)
Hematologic Neoplasms (Phase 2)
Hemorrhage (Phase 4)
Hemorrhagic Fever, Ebola (Phase 3)
Hemorrhagic Fevers, Viral (Phase 3)
Hepatitis (Phase 4)
Hepatitis A (Phase 4)
Hepatitis B (Phase 3)
Hepatitis B, Chronic (Phase 3)
Hepatitis C (Phase 4)
Hepatitis C, Chronic (Phase 4)
Hepatitis, Chronic (Phase 3)
Hepatitis D (Phase 2)
Hepatitis D, Chronic (Phase 2)
Herpesviridae Infections (Phase 2)
Hidradenitis (Phase 1)
Hidradenitis Suppurativa (Phase 1)
Histoplasmosis (Phase 3)
HIV Infections (Phase 4)
HIV Seropositivity (Phase 4)
Hypergammaglobulinemia (Phase 2)
Hyperkinesis (Phase 4)
Hypersensitivity (Phase 4)
Hypertension (Phase 4)
Hypertension, Pulmonary (Phase 3)
Hypertrophy (Phase 3)
Hypertrophy, Left Ventricular (Phase 3)
Ichthyosis (Phase 1)
Ichthyosis, Lamellar (Phase 1)
Immunoglobulin Light-chain Amyloidosis (Phase 2)
Immunologic Deficiency Syndromes (Phase 4)
Infections (Phase 4)
Inflammation (Phase 4)
Inflammatory Bowel Diseases (Phase 4)
Influenza, Human (Phase 2)
Intervertebral Disc Degeneration (Phase 2)
Intestinal Diseases (Phase 4)
Invasive Fungal Infections (Phase 4)
Ischemia (Phase 2)
Ischemic Attack, Transient (Phase 2)
Kidney Diseases (Phase 3)
Kidney Failure, Chronic (Phase 4)
Labyrinth Diseases (Phase 2)
Labyrinthitis (Phase 2)
Leiomyosarcoma (Phase 1)
Leukemia (Phase 3)
Leukemia, Lymphocytic, Chronic, B-Cell (Phase 3)
Leukemia, Lymphoid (Phase 3)
Leukemia, Myeloid (Phase 2)
Leukemia, Myeloid, Acute (Phase 3)
Leukemia, Myelomonocytic, Chronic (Phase 2)
Leukemia, Myelomonocytic, Juvenile (Phase 2)
Liposarcoma (Phase 2)
Liposarcoma, Myxoid (Phase 2)
Liver Cirrhosis (Phase 3)
Liver Diseases (Phase 1)
Liver Neoplasms (Phase 2)
Low Back Pain (Phase 4)
Lung Diseases (Phase 3)
Lung Neoplasms (Phase 4)
Lupus Erythematosus, Systemic (Phase 3)
Lupus Nephritis (Phase 2)
Lymphoma (Phase 3)
Lymphoma, B-Cell (Phase 3)
Lymphoma, B-Cell, Marginal Zone (Phase 2)
Lymphoma, Follicular (Phase 2)
Lymphoma, Large B-Cell, Diffuse (Phase 3)
Lymphoma, Mantle-Cell (Phase 3)
Lymphoma, Non-Hodgkin (Phase 1)
Lymphoma, T-Cell (Phase 2)
Lymphoma, T-Cell, Peripheral (Phase 2)
Malnutrition (Phase 1)
Mental Disorders (Phase 4)
Migraine Disorders (Phase 4)
Migraine with Aura (Phase 4)
Migraine without Aura (Phase 4)
Multiple Chronic Conditions (Phase 3)
Multiple Myeloma (Phase 3)
Mycobacterium Infections (Phase 3)
Mycoses (Phase 4)
Myelodysplastic Syndromes (Phase 2)
Myocardial Ischemia (Phase 4)
Necrosis (Phase 3)
Neoplasm Metastasis (Phase 2)
Neoplasms (Phase 2)
Neoplasms, Plasma Cell (Phase 3)
Neoplastic Cells, Circulating (Phase 2)
Nephritis (Phase 2)
Nervous System Diseases (Phase 2)
Neuralgia (Phase 3)
Neuralgia, Postherpetic (Phase 3)
Neutropenia (Phase 3)
Obsessive-Compulsive Disorder (Phase 4)
Onychomycosis (Phase 4)
Optic Nerve Glioma (Phase 2)
Osteoarthritis (Phase 4)
Osteoarthritis, Knee (Phase 4)
Ovarian Neoplasms (Phase 2)
Overweight (Phase 4)
Pain, Intractable (Phase 3)
Pain, Postoperative (Phase 4)
Panic Disorder (Phase 4)
Papilloma (Phase 4)
Papillomavirus Infections (Phase 2)
Paraproteinemias (Phase 2)
Parasomnias (Phase 4)
Peptic Ulcer (Phase 4)
Peptic Ulcer Hemorrhage (Phase 4)
Peripheral Arterial Disease (Phase 4)
Peripheral Nervous System Diseases (Phase 4)
Peripheral Vascular Diseases (Phase 4)
Personality Disorders (Phase 4)
Pharyngitis (Phase 3)
Philadelphia Chromosome (Phase 1)
Phobia, Social (Phase 4)
Phobic Disorders (Phase 4)
Plasmacytoma (Phase 2)
POEMS Syndrome (Phase 2)
Polymyalgia Rheumatica (Phase 2)
Polymyositis (Phase 3)
Pouchitis (Phase 3)
Preleukemia (Phase 2)
Problem Behavior (Phase 3)
Prostatic Neoplasms (Phase 4)
Psoriasis (Phase 4)
Psychomotor Agitation (Phase 4)
Psychotic Disorders (Phase 4)
Pulmonary Embolism (Phase 4)
Pyelonephritis (Phase 4)
Recurrence (Phase 3)
Reflex Sympathetic Dystrophy (Phase 3)
Renal Insufficiency (Phase 4)
Renal Insufficiency, Chronic (Phase 4)
Respiratory Syncytial Virus Infections (Phase 2)
Respiratory Tract Diseases (Phase 2)
Respiratory Tract Infections (Phase 2)
Rett Syndrome (Phase 3)
Salivary Gland Neoplasms (Phase 2)
Sarcoma (Phase 2)
Sarcoma, Ewing (Phase 1)
Schizophrenia (Phase 4)
Scleroderma, Diffuse (Phase 2)
Scleroderma, Systemic (Phase 2)
Seizures (Phase 3)
Sleep Wake Disorders (Phase 4)
Smoldering Multiple Myeloma (Phase 2)
Somatoform Disorders (Phase 3)
Spondylarthritis (Phase 3)
Stress Disorders, Post-Traumatic (Phase 4)
Stress Disorders, Traumatic (Phase 4)
Stroke (Phase 3)
Substance-Related Disorders (Phase 4)
Syndrome (Phase 3)
Tauopathies (Phase 2)
Thromboembolism (Phase 3)
Thrombosis (Phase 4)
Triple Negative Breast Neoplasms (Phase 2)
Tuberculosis (Phase 3)
Tuberculosis, Multidrug-Resistant (Phase 3)
Ulcer (Phase 4)
Urinary Bladder Neoplasms (Phase 3)
Urinary Bladder, Overactive (Phase 4)
Venous Thromboembolism (Phase 3)
Venous Thrombosis (Phase 4)
Viremia (Phase 4)
Virus Diseases (Phase 3)
Waldenstrom Macroglobulinemia (Phase 4)
Weight Gain (Phase 4)
Weight Loss (Phase 4)