Organization | Endo Pharmaceuticals

Endo Pharmaceuticals Report issue

Contributed to NME For profit Phase 1 Phase 2 Phase 3 Phase 4

Founded: Malvern PA United States (1997)

Status: Acquired by DuPont (1970) → now Bristol-Myers Squibb (2001)

Organization Overview

First Clinical Trial

1997

NCT01316874

First Marketed Drug

1997

acetylsalicylic acid (aspirin)

First NDA Approval

None

Last Known Activity

2023

Timeline

NOW

Now

Mergers & Acquisitions

Historical Acquisition Tree

Alternative names

Endo | Endo Global Aesthetics Limited | ENDO GLOBAL AESTHETICS LTD | ENDO PHARM | Endo Pharmaceuticals | Endo Pharmaceuticals (formerly Valera/Indevus Pharmaceuticals) | EndoPharmceuticals | Endo Pharmceuticals | ENDO PHARMS | ENDO PHARMS INC | Endo (v1) | Endo (v2) | ENDO VENTURES | ENDO VENTURES LTD

Active Ingredients

Marketed Drugs (20)

Key: Endo Pharmaceuticals (16) Acquired (4)

acetylsalicylic acid (aspirin) (1950)

amantadine (symmetrel) (1968 NDA)

anisotropine methylbromide (valpin) (1962 NDA)

colistin (1962)

collagenase clostridium histolyticum (xiaflex) (2020)

cyanocobalamin (berocca) (2005)

ephedrine (2020)

frovatriptan (frova) (2001)

histrelin (supprelin) (2004)

megestrol (megace) (2005)

molindone (moban) (1974 NDA)

neomycin (1962)

oxycodone (oxycontin) (1950)

oxymorphone (opana) (1959 NDA)

sumatriptan (zecuity) (2009)

testosterone (delatestryl) (1953 NDA)

thonzonium bromide (1962 NDA)

urea (1962)

valganciclovir (Valcyte) (2014)

valrubicin (valstar) (1998)

Drugs in Phase 4 Trials (16)

Key: Endo Pharmaceuticals (12) Acquired (4)

acetaminophen (tylenol) (5 trials)

arnica (1 trial)

celecoxib (celebrex) (2 trials)

collagenase clostridium histolyticum (xiaflex) (51 trials)

diclofenac (voltaren) (2 trials)

frovatriptan (frova) (6 trials)

gabapentin (neurontin) (1 trial)

hydromorphone (diladid) (1 trial)

lidocaine (xylocaine) (16 trials)

oxycodone (oxycontin) (3 trials)

oxymorphone (opana) (18 trials)

propoxyphene (Darvon) (1 trial)

tacrolimus (prograf) (2 trials)

testosterone (delatestryl) (8 trials)

tetracaine (pontocaine) (1 trial)

topiramate (topamax) (1 trial)

Drugs in Phase 3 Trials (28)

Key: Endo Pharmaceuticals (8) Acquired (20)

acetylcysteine (mucomyst) (2 trials)

apomorphine (apokyn) (1 trial)

buprenorphine (2 trials)

ciprofloxacin (cipro) (2 trials)

davunetide (3 trials)

goserelin (zoladex) (1 trial)

histrelin (supprelin) (3 trials)

inactivated influenza vaccine (11 trials)

ketoprofen (orudis) (5 trials)

lubiprostone (amitiza) (1 trial)

megestrol (megace) (5 trials)

mrna-1010 (12 trials)

mrna-1083 (2 trials)

mrna-1273 (Spikevax) (20 trials)

mrna-1345 (10 trials)

mrna-1647 (9 trials)

mrna-4157 (4 trials)

octreotide (sandostatin) (4 trials)

ondansetron (zofran) (6 trials)

pagoclone (3 trials)

pembrolizumab (keytruda) (5 trials)

pimecrolimus (elidel) (1 trial)

sumatriptan (zecuity) (8 trials)

tenofovir (viread) (1 trial)

tramadol (Ultram) (17 trials)

trazodone (desyrel) (5 trials)

urea (2 trials)

valrubicin (valstar) (3 trials)

Drugs in Phase 2 Trials (31)

Key: Endo Pharmaceuticals (5) Acquired (26)

alendronic acid (fosamax) (1 trial)

amphotericin b (fungizone) (1 trial)

darolutamide (Nubeqa) (2 trials)

ethanol (1 trial)

finasteride (Proscar) (1 trial)

fluarix (1 trial)

miltefosine (impavido) (1 trial)

morphine (1 trial)

mrna-1010.6 (1 trial)

mrna-1018 (1 trial)

mrna-1073 (1 trial)

mRNA-1283 (2 trials)

mrna-1325 (1 trial)

mrna-1468 (1 trial)

mrna-1608 (1 trial)

mrna-1769 (1 trial)

mrna-1893 (2 trials)

mrna-1975 (1 trial)

mrna-1982 (1 trial)

mrna-3210 (1 trial)

mrna-3704 (1 trial)

mrna-3705 (2 trials)

mrna-3927 (2 trials)

mrna-4359 (1 trial)

propranolol (inderal) (2 trials)

serogroup B meningococcal vaccine (Bexsero) (1 trial)

sodium stibogluconate (Pentostam) (1 trial)

trospium (sanctura) (1 trial)

Tuberculin, Purified Protein Derivative (Tubersol) (3 trials)

varicella zoster virus glycoprotein e antigen (Shingrix) (1 trial)

vitamin e (2 trials)

Drugs in Phase 1 Trials (37)

Key: Endo Pharmaceuticals (2) Acquired (35)

buspirone (buspar) (2 trials)

cabergoline (dostinex) (2 trials)

clonazepam (klonopin) (2 trials)

core-g28v2 60mer mrna vaccine (1 trial)

doxycycline (vibramycin) (5 trials)

dronabinol (marinol) (1 trial)

durvalumab (imfinzi) (2 trials)

eod-gt8 60mer (2 trials)

leflunomide (arava) (2 trials)

lisinopril (zestril) (2 trials)

Meningococcal (Groups A, C, Y, W) Conjugate Vaccine (MenQuadfi) (1 trial)

metronidazole (flagyl) (2 trials)

mrna-0184 (1 trial)

mrna-1045 (1 trial)

mrna-1189 (2 trials)

mrna-1195 (1 trial)

mrna-1230 (1 trial)

mrna-1365 (1 trial)

mrna-1403 (1 trial)

mrna-1405 (1 trial)

mrna-1443 (1 trial)

mrna-1653 (2 trials)

mrna-1944 (1 trial)

mrna-2416 (1 trial)

mrna-2736 (1 trial)

mrna-2752 (1 trial)

mrna-3745 (1 trial)

mrna-6231 (1 trial)

oxandrolone (oxandrin) (1 trial)

risperidone (risperdal) (1 trial)

sodium chloride (1 trial)

torsemide (demadex) (2 trials)

tranylcypromine (parnate) (1 trial)

val-181388 (1 trial)

val-339851 (1 trial)

val-506440 (1 trial)

vasopressin (vasostrict) (1 trial)

Indications

Approved Indications

Influenza, Human

Intracranial Arteriosclerosis

Irritable Bowel Syndrome

Klinefelter Syndrome

Parkinson Disease

Parkinson Disease, Postencephalitic

Parkinson Disease, Secondary

Postpoliomyelitis Syndrome

Experimental Indications (Clinical Trials, Phases 1-4)

Acquired Immunodeficiency Syndrome (Phase 3)

Acromegaly (Phase 3)

Acute Pain (Phase 3)

Adenocarcinoma (Phase 3)

Ankle Injuries (Phase 3)

Anorexia (Phase 2)

Atrophy (Phase 2)

Back Pain (Phase 4)

Bone Diseases, Metabolic (Phase 2)

Breakthrough Pain (Phase 4)

Bursitis (Phase 3)

Cachexia (Phase 2)

Carcinoid Tumor (Phase 2)

Carcinoma (Phase 3)

Carcinoma in Situ (Phase 3)

Carcinoma, Transitional Cell (Phase 3)

Cardiovascular Diseases (Phase 4)

Carpal Tunnel Syndrome (Phase 4)

Cellulite (Phase 3)

Chlamydia Infections (Phase 3)

Chronic Disease (Phase 3)

Chronic Pain (Phase 4)

Communicable Diseases (Phase 3)

Complex Regional Pain Syndromes (Phase 4)

Constriction, Pathologic (Phase 4)

Contracture (Phase 4)

Dermatitis (Phase 3)

Dermatitis, Atopic (Phase 3)

Diabetic Neuropathies (Phase 4)

Dupuytren Contracture (Phase 4)

Eczema (Phase 3)

Edema (Phase 3)

Eunuchism (Phase 4)

Gonorrhea (Phase 3)

Headache (Phase 4)

Head and Neck Neoplasms (Phase 3)

Herpes Genitalis (Phase 3)

HIV Infections (Phase 3)

HIV Wasting Syndrome (Phase 2)

Hypertrophy (Phase 2)

Hypogonadism (Phase 4)

Infections (Phase 3)

Low Back Pain (Phase 4)

Lung Diseases (Phase 2)

Lung Diseases, Obstructive (Phase 2)

Malignant Carcinoid Syndrome (Phase 2)

Migraine Disorders (Phase 4)

Mucositis (Phase 3)

Multiple Sclerosis (Phase 4)

Muscular Atrophy (Phase 2)

Neuralgia (Phase 4)

Neuralgia, Postherpetic (Phase 4)

Osteoarthritis (Phase 4)

Osteoarthritis, Knee (Phase 4)

Osteoporosis (Phase 2)

Pain, Postoperative (Phase 3)

Penile Induration (Phase 4)

Peripheral Nervous System Diseases (Phase 4)

Premature Birth (Phase 2)

Premature Ejaculation (Phase 2)

Premenstrual Syndrome (Phase 4)

Prostatic Neoplasms (Phase 3)

Puberty, Precocious (Phase 3)

Pulmonary Disease, Chronic Obstructive (Phase 2)

Recurrence (Phase 4)

Reflex Sympathetic Dystrophy (Phase 4)

Sarcopenia (Phase 2)

Schizophrenia (Phase 1)

Sclerosis (Phase 4)

Serotonin Syndrome (Phase 2)

Spinal Stenosis (Phase 4)

Sprains and Strains (Phase 3)

Stomatitis (Phase 3)

Stuttering (Phase 3)

Syndrome (Phase 4)

Tendinopathy (Phase 3)

Wasting Syndrome (Phase 2)

Weight Gain (Phase 2)

Overview

Highest Phase: Phase 4
# of Trials: 291
# of Trial APIs: 112