Cubist   Report issue

Contributed to NME For profit Phase 1 Phase 2 Phase 3 Phase 4
Founded: Lexington MA United States (1992)
Status: Acquired by Merck (2014)

Organization Overview

First Clinical Trial
2000
NCT00538694
First Marketed Drug
2003
daptomycin (cubicin)
First NDA Approval
2003
daptomycin (cubicin)
Last Known Activity
2015

Timeline

NOW
  • Now

Mergers & Acquisitions

Historical Acquisition Tree

Alternative names

Cubist Pharmaceuticals, 65 Hayden Ave, Lexington, MA 02421, USA | Cubist Pharmaceuticals LLC | CUBIST PHARMS | CUBIST PHARMS LLC

Active Ingredients

Marketed Drugs (6)

Key: Cubist (4) Acquired (2)

alvimopan (entereg) (2008)

ceftolozane (Zerbaxa) (2014)

daptomycin (cubicin) (2003 NDA)

fidaxomicin (dificid) (2011)

tazobactam (Zosyn) (2014)

tedizolid phosphate (sivextro) (2014 NDA)

Drugs in Phase 4 Trials (10)

Key: Cubist (8) Acquired (2)

alvimopan (entereg) (14 trials)

ceftolozane (Zerbaxa) (10 trials)

cloxacillin (pathocil) (1 trial)

daptomycin (cubicin) (35 trials)

fidaxomicin (dificid) (10 trials)

gentamicin (garamycin) (1 trial)

nafcillin (unipen) (3 trials)

oxacillin (pathocil) (2 trials)

tazobactam (Zosyn) (7 trials)

vancomycin (Vancocin) (20 trials)

Drugs in Phase 3 Trials (15)

Key: Cubist (11) Acquired (4)

amphetamine (Adderall) (1 trial)

bevenopran (7 trials)

cefazolin (ancef) (1 trial)

cephalexin (keflex) (1 trial)

clindamycin (cleocin) (1 trial)

flucloxacillin (2 trials)

levofloxacin (levaquin) (1 trial)

linezolid (zyvox) (5 trials)

meropenem (merrem) (3 trials)

metronidazole (flagyl) (2 trials)

piperacillin (pipracil) (1 trial)

prulifloxacin (1 trial)

sodium chloride (1 trial)

streptomycin (kabikinase) (3 trials)

tedizolid phosphate (sivextro) (20 trials)

Drugs in Phase 2 Trials (13)

adl 5747 (2 trials)

adl5859 (4 trials)

ceftazidime (fortaz) (1 trial)

duloxetine (Cymbalta) (1 trial)

ecallantide (Kalbitor) (3 trials)

exbivirumab (1 trial)

hepatitis b immune globulin (human) (BayHep B) (1 trial)

ibuprofen (motrin) (1 trial)

naproxen (naprosyn) (1 trial)

oxycodone (oxycontin) (1 trial)

pregabalin (lyrica) (1 trial)

teicoplanin (1 trial)

tranexamic acid (cyklokapron) (1 trial)

Drugs in Phase 1 Trials (5)

Key: Cubist (3) Acquired (2)

cb-238,618 (1 trial)

moxifloxacin (avelox) (2 trials)

rifampin (1 trial)

rosuvastatin (crestor) (1 trial)

tyramine (1 trial)

Drugs in Other Trials (1)

polyethylene (1 trial)

Indications

Approved Indications


 

Infections

Skin Diseases, Bacterial

Skin Diseases, Infectious

Staphylococcal Skin Infections

Staphylococcus aureus

Experimental Indications (Clinical Trials, Phases 1-4)


 

Acute Pain (Phase 2)

Arthritis (Phase 2)

Arthritis, Rheumatoid (Phase 2)

Bacteremia (Phase 4)

Bacterial Infections (Phase 3)

Blood Loss, Surgical (Phase 2)

Cancer Pain (Phase 2)

Cellulitis (Phase 4)

Clostridium Infections (Phase 4)

Communicable Diseases (Phase 4)

Constipation (Phase 3)

Critical Illness (Phase 4)

Cystic Fibrosis (Phase 4)

Diabetic Foot (Phase 4)

Diarrhea (Phase 3)

Endocarditis (Phase 4)

Endocarditis, Bacterial (Phase 4)

End Stage Liver Disease (Phase 2)

Erysipelas (Phase 4)

Fallopian Tube Neoplasms (Phase 3)

Febrile Neutropenia (Phase 3)

Fibrosis (Phase 4)

Gastrointestinal Diseases (Phase 3)

Gram-Negative Bacterial Infections (Phase 1)

Gram-Positive Bacterial Infections (Phase 3)

Healthcare-Associated Pneumonia (Phase 3)

Hemorrhage (Phase 2)

Hepatitis (Phase 2)

Hepatitis A (Phase 2)

Hepatitis B (Phase 2)

Ileus (Phase 4)

Infections (Phase 4)

Intestinal Diseases (Phase 3)

Intraabdominal Infections (Phase 3)

Kidney Diseases (Phase 2)

Kidney Failure, Chronic (Phase 2)

Liver Diseases (Phase 2)

Lung Diseases (Phase 3)

Neuralgia (Phase 2)

Neuralgia, Postherpetic (Phase 2)

Neutropenia (Phase 3)

Osteoarthritis (Phase 2)

Osteoarthritis, Knee (Phase 2)

Osteomyelitis (Phase 3)

Peripheral Nervous System Diseases (Phase 2)

Pneumonia (Phase 3)

Pneumonia, Bacterial (Phase 3)

Pneumonia, Ventilator-Associated (Phase 3)

Pseudomonas Infections (Phase 4)

Pulmonary Fibrosis (Phase 4)

Pyelonephritis (Phase 3)

Renal Insufficiency (Phase 4)

Skin Diseases (Phase 4)

Skin Diseases, Bacterial (Phase 4)

Skin Diseases, Infectious (Phase 4)

Soft Tissue Infections (Phase 4)

Spinal Cord Injuries (Phase 4)

Staphylococcal Infections (Phase 4)

Staphylococcal Skin Infections (Phase 4)

Surgical Wound (Phase 4)

Surgical Wound Infection (Phase 4)

Urinary Tract Infections (Phase 3)

Wound Infection (Phase 4)

Wounds and Injuries (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 111
  • # of Trial APIs: 44