Organization | Dutch Childhood Oncology Group

Dutch Childhood Oncology Group Report issue

Academic/Hospital Phase 2 Phase 3

Founded: The Hague Netherlands (2002)

Organization Overview

First Clinical Trial

2002

NCT00015873

First Marketed Drug

None

First NDA Approval

None

Last Known Activity

2020

Timeline

NOW

Now

Alternative names

Dutch Childhood Oncology Group- Early Clinical Trial Consortium

Active Ingredients

Drugs in Phase 3 Trials (20)

asparaginase (elspar) (2 trials)

busulfan (Myleran) (2 trials)

carboplatin (paraplatin) (1 trial)

cyclophosphamide (cytoxan) (3 trials)

cytarabine (cytosar-u) (3 trials)

dactinomycin (cosmegen) (1 trial)

daunorubicin (cerubidine) (2 trials)

doxorubicin (Doxil) (2 trials)

etoposide (vepesid) (3 trials)

fludarabine (fludara) (1 trial)

hemopoietic stem cell (1 trial)

ifosfamide (ifex) (2 trials)

melphalan (alkeran) (2 trials)

mercaptopurine (purinethol) (2 trials)

naltrexone (revia) (2 trials)

prednisone (meticorten) (2 trials)

tioguanine (Lanvis) (2 trials)

topotecan (hycamtin) (1 trial)

vincristine (oncovin) (3 trials)

vinorelbine (navelbine) (1 trial)

Drugs in Phase 2 Trials (1)

bosutinib (bosulif) (1 trial)

Drugs in Other Trials (8)

allogeneic hematopoietic stem cells (Hemacord) (1 trial)

Anti-thymocyte Globulin (Rabbit) (Thymoglobulin) (1 trial)

autologous umbilical cord blood (1 trial)

cyclosporine (sandimmune) (1 trial)

leucovorin (1 trial)

mitoxantrone (novantrone) (1 trial)

pegaspargase (oncaspar) (1 trial)

Indications

Experimental Indications (Clinical Trials, Phases 1-4)

Blast Crisis (Phase 2)

Histiocytoma (Phase 3)

Histiocytoma, Benign Fibrous (Phase 3)

Histiocytoma, Malignant Fibrous (Phase 3)

Leukemia (Phase 3)

Leukemia, Lymphoid (Phase 3)

Leukemia, Myelogenous, Chronic, BCR-ABL Positive (Phase 2)

Leukemia, Myeloid (Phase 3)

Leukemia, Myeloid, Accelerated Phase (Phase 2)

Leukemia, Myeloid, Acute (Phase 3)

Leukemia, Myeloid, Chronic-Phase (Phase 2)

Philadelphia Chromosome (Phase 2)

Precursor Cell Lymphoblastic Leukemia-Lymphoma (Phase 3)

Rhabdomyosarcoma (Phase 3)

Sarcoma (Phase 3)

Overview

Highest Phase: Phase 3
# of Trials: 6
# of Trial APIs: 29