Related MeSH Hierarchy (4)
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Membrane Proteins » Receptors, Cell Surface » Receptors, Immunologic » Costimulatory and Inhibitory T-Cell Receptors » CTLA-4 Antigen
Chemicals and Drugs [D] » Biological Factors [D23] » Antigens » Antigens, Surface » Antigens, Differentiation » Antigens, Differentiation, T-Lymphocyte » CTLA-4 Antigen
Chemicals and Drugs [D] » Biological Factors [D23] » Biomarkers » Antigens, Differentiation » Antigens, Differentiation, T-Lymphocyte » CTLA-4 Antigen
Chemicals and Drugs [D] » Amino Acids, Peptides, and Proteins [D12] » Proteins » Immune Checkpoint Proteins » CTLA-4 Antigen
Description
An inhibitory T CELL receptor that is closely related to CD28 ANTIGEN. It has specificity for CD80 ANTIGEN and CD86 ANTIGEN and acts as a negative regulator of peripheral T cell function. CTLA-4 antigen is believed to play role in inducing PERIPHERAL TOLERANCE. MeSH
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