Related MeSH Hierarchy (5)
Diseases [C] » Hemic and Lymphatic Diseases [C15] » Hematologic Diseases » Blood Protein Disorders » Dysgammaglobulinemia » Hyper-IgM Immunodeficiency Syndrome
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Genetic Diseases, Inborn » Hyper-IgM Immunodeficiency Syndrome
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Genetic Diseases, Inborn » Primary Immunodeficiency Diseases » Hyper-IgM Immunodeficiency Syndrome
Diseases [C] » Immune System Diseases [C20] » Immunologic Deficiency Syndromes » Dysgammaglobulinemia » Hyper-IgM Immunodeficiency Syndrome
Diseases [C] » Immune System Diseases [C20] » Immunologic Deficiency Syndromes » Primary Immunodeficiency Diseases » Hyper-IgM Immunodeficiency Syndrome
Description
A rare inherited immunodeficiency syndrome characterized by normal or elevated serum IMMUNOGLOBULIN M levels with absence of IMMUNOGLOBULIN G; IMMUNOGLOBULIN A; and IMMUNOGLOBULIN E. It results in a profound susceptibility to BACTERIAL INFECTIONS and an increased susceptibility to OPPORTUNISTIC INFECTIONS. Several subtypes of hyper-IgM immunodeficiency syndrome exist depending upon the location of genetic mutation. MeSH
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Subtype Terms (1)
Hyper-IgM Immunodeficiency Syndrome, Type 1
9 approved drugs
Phase 4 Indicated Drugs (1)
Other Experimental Indicated Drugs (7)
Organization Involved with Phase 4 Indications (1)
Organization Involved with Phase 3 Indications (1)
Organization Involved with Phase 2 Indications (1)
Organization Involved with Other Experimental Indications (1)
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