Optic Atrophy, Hereditary, Leber D029242

Related MeSH Hierarchy (7)

Diseases [C] » Eye Diseases [C11] » Eye Diseases, Hereditary » Optic Atrophies, Hereditary » Optic Atrophy, Hereditary, Leber

Diseases [C] » Eye Diseases [C11] » Optic Nerve Diseases » Optic Atrophy » Optic Atrophies, Hereditary » Optic Atrophy, Hereditary, Leber

Diseases [C] » Nervous System Diseases [C10] » Cranial Nerve Diseases » Optic Nerve Diseases » Optic Atrophy » Optic Atrophies, Hereditary » Optic Atrophy, Hereditary, Leber

Diseases [C] » Nutritional and Metabolic Diseases [C18] » Metabolic Diseases » Mitochondrial Diseases » Optic Atrophy, Hereditary, Leber

Description

A maternally linked genetic disorder that presents in mid-life as acute or subacute central vision loss leading to central scotoma and blindness. The disease has been associated with missense mutations in the mtDNA, in genes for Complex I, III, and IV polypeptides, that can act autonomously or in association with each other to cause the disease. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/Omim/, MIM#535000 (April 17, 2001))   MeSH

Phase 4 Indicated Drugs (1)

Phase 3 Indicated Drugs (3)

Other Experimental Indicated Drugs (1)


Organization Involved with Phase 4 Indications (1)

Organization Involved with Phase 1 Indications (2)

Organization Involved with Other Experimental Indications (1)

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UMLS Data


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