Lewy Body Disease D020961

Related MeSH Hierarchy (5)

Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Brain Diseases » Dementia » Lewy Body Disease

Diseases [C] » Nervous System Diseases [C10] » Neurodegenerative Diseases » Synucleinopathies » Lewy Body Disease

Psychiatry and Psychology [F] » Mental Disorders [F03] » Neurocognitive Disorders » Dementia » Lewy Body Disease

Description

A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)   MeSH

Other Experimental Indicated Drugs (2)


Organization Involved with Phase 3 Indications (4)

Organization Involved with Phase 1 Indications (1)

Organization Involved with Other Experimental Indications (3)

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