Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Brain Diseases » Dementia » Frontotemporal Lobar Degeneration » Frontotemporal Dementia » Pick Disease of the Brain
Psychiatry and Psychology [F] » Mental Disorders [F03] » Neurocognitive Disorders » Dementia » Frontotemporal Lobar Degeneration » Frontotemporal Dementia » Pick Disease of the Brain
Description
A rare form of DEMENTIA that is sometimes familial. Clinical features include APHASIA; APRAXIA; CONFUSION; ANOMIA; memory loss; and personality deterioration. This pattern is consistent with the pathologic findings of circumscribed atrophy of the poles of the FRONTAL LOBE and TEMPORAL LOBE. Neuronal loss is maximal in the HIPPOCAMPUS, entorhinal cortex, and AMYGDALA. Some ballooned cortical neurons contain argentophylic (Pick) bodies. (From Brain Pathol 1998 Apr;8(2):339-54; Adams et al., Principles of Neurology, 6th ed, pp1057-9) MeSH
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Phase 2 Indicated Drugs (1)
Phase 1 Indicated Drugs (1)
Other Experimental Indicated Drugs (1)
Organization Involved with Phase 4 Indications (8)
Organization Involved with Phase 3 Indications (7)
Organization Involved with Phase 2 Indications (28)
Organization Involved with Phase 1 Indications (14)
Organization Involved with Other Experimental Indications (2)
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