Related MeSH Hierarchy (4)
Diseases [C] » Nervous System Diseases [C10] » Autonomic Nervous System Diseases » Primary Dysautonomias » Multiple System Atrophy
Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Brain Diseases » Basal Ganglia Diseases » Multiple System Atrophy
Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Movement Disorders » Multiple System Atrophy
Diseases [C] » Nervous System Diseases [C10] » Neurodegenerative Diseases » Synucleinopathies » Multiple System Atrophy
Description
A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92) MeSH
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Subtype Terms (3)
Shy-Drager Syndrome
7 drugs (5 approved, 2 experimental)
Approved Indicated Drugs (1)
Phase 4 Indicated Drugs (2)
Phase 3 Indicated Drugs (5)
Phase 2 Indicated Drugs (17)
Phase 1 Indicated Drugs (15)
Other Experimental Indicated Drugs (11)
Organization Involved with Phase 4 Indications (2)
Organization Involved with Phase 3 Indications (24)
Organization Involved with Phase 2 Indications (13)
Organization Involved with Phase 1 Indications (12)
Organization Involved with Other Experimental Indications (5)
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UMLS Data
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