Area Under Curve D019540

Related MeSH Hierarchy (4)

Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E] » Investigative Techniques [E05] » Epidemiologic Methods » Statistics as Topic » Area Under Curve

Phenomena and Processes [G] » Metabolism [G03] » Pharmacokinetics » Area Under Curve

Phenomena and Processes [G] » Physiological Phenomena [G07] » Pharmacological and Toxicological Phenomena » Pharmacokinetics » Area Under Curve

Health Care [N] » Environment and Public Health [N06] » Public Health » Epidemiologic Methods » Statistics as Topic » Area Under Curve

Description

A statistical means of summarizing information from a series of measurements on one individual. It is frequently used in clinical pharmacology where the AUC from serum levels can be interpreted as the total uptake of whatever has been administered. As a plot of the concentration of a drug against time, after a single dose of medicine, producing a standard shape curve, it is a means of comparing the bioavailability of the same drug made by different companies. (From Winslade, Dictionary of Clinical Research, 1992)   MeSH

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