Optic Neuropathy, Ischemic D018917

Diseases [C] » Cardiovascular Diseases [C14] » Vascular Diseases » Optic Neuropathy, Ischemic

Diseases [C] » Nervous System Diseases [C10] » Cranial Nerve Diseases » Optic Nerve Diseases » Optic Neuropathy, Ischemic

Diseases [C] » Eye Diseases [C11] » Optic Nerve Diseases » Optic Neuropathy, Ischemic

Description

Ischemic injury to the OPTIC NERVE which usually affects the OPTIC DISK (optic neuropathy, anterior ischemic) and less frequently the retrobulbar portion of the nerve (optic neuropathy, posterior ischemic). The injury results from occlusion of arterial blood supply which may result from TEMPORAL ARTERITIS; ATHEROSCLEROSIS; COLLAGEN DISEASES; EMBOLISM; DIABETES MELLITUS; and other conditions. The disease primarily occurs in the sixth decade or later and presents with the sudden onset of painless and usually severe monocular visual loss. Anterior ischemic optic neuropathy also features optic disk edema with microhemorrhages. The optic disk appears normal in posterior ischemic optic neuropathy. (Glaser, Neuro-Ophthalmology, 2nd ed, p135)   MeSH

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Phase 1 Indicated Drugs (3)

Other Experimental Indicated Drugs (3)


Organization Involved with Phase 1 Indications (4)

Organization Involved with Other Experimental Indications (2)

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