Related MeSH Hierarchy (5)
Diseases [C] » Neoplasms [C04] » Neoplasms by Site » Endocrine Gland Neoplasms » Multiple Endocrine Neoplasia » Multiple Endocrine Neoplasia Type 1
Diseases [C] » Neoplasms [C04] » Neoplasms, Multiple Primary » Multiple Endocrine Neoplasia » Multiple Endocrine Neoplasia Type 1
Diseases [C] » Neoplasms [C04] » Neoplastic Syndromes, Hereditary » Multiple Endocrine Neoplasia » Multiple Endocrine Neoplasia Type 1
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Genetic Diseases, Inborn » Neoplastic Syndromes, Hereditary » Multiple Endocrine Neoplasia » Multiple Endocrine Neoplasia Type 1
Diseases [C] » Endocrine System Diseases [C19] » Endocrine Gland Neoplasms » Multiple Endocrine Neoplasia » Multiple Endocrine Neoplasia Type 1
Description
A form of multiple endocrine neoplasia that is characterized by the combined occurrence of tumors in the PARATHYROID GLANDS, the PITUITARY GLAND, and the PANCREATIC ISLETS. The resulting clinical signs include HYPERPARATHYROIDISM; HYPERCALCEMIA; HYPERPROLACTINEMIA; CUSHING DISEASE; GASTRINOMA; and ZOLLINGER-ELLISON SYNDROME. This disease is due to loss-of-function of the MEN1 gene, a tumor suppressor gene (GENES, TUMOR SUPPRESSOR) on CHROMOSOME 11 (Locus: 11q13). MeSH
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Phase 1 Indicated Drugs (3)
Other Experimental Indicated Drugs (1)
Organization Involved with Phase 2 Indications (2)
Organization Involved with Phase 1 Indications (1)
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UMLS Data
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