Related MeSH Hierarchy (5)
Diseases [C] » Neoplasms [C04] » Neoplasms by Histologic Type » Neoplasms, Connective and Soft Tissue » Neoplasms, Connective Tissue » Neoplasms, Fibrous Tissue » Fibrosarcoma » Neurofibrosarcoma
Diseases [C] » Neoplasms [C04] » Neoplasms by Histologic Type » Neoplasms, Connective and Soft Tissue » Sarcoma » Fibrosarcoma » Neurofibrosarcoma
Diseases [C] » Neoplasms [C04] » Neoplasms by Histologic Type » Neoplasms, Nerve Tissue » Nerve Sheath Neoplasms » Neurofibroma » Neurofibrosarcoma
Diseases [C] » Nervous System Diseases [C10] » Nervous System Neoplasms » Peripheral Nervous System Neoplasms » Nerve Sheath Neoplasms » Neurofibroma » Neurofibrosarcoma
Diseases [C] » Nervous System Diseases [C10] » Neuromuscular Diseases » Peripheral Nervous System Diseases » Peripheral Nervous System Neoplasms » Nerve Sheath Neoplasms » Neurofibroma » Neurofibrosarcoma
Description
A malignant tumor that arises from small cutaneous nerves, is locally aggressive, and has a potential for metastasis. Characteristic histopathologic features include proliferating atypical spindle cells with slender wavy and pointed nuclei, hypocellular areas, and areas featuring organized whorls of fibroblastic proliferation. The most common primary sites are the extremities, retroperitoneum, and trunk. These tumors tend to present in childhood, often in association with NEUROFIBROMATOSIS 1. (From DeVita et al., Cancer: Principles & Practice of Oncology, 5th ed, p1662; Mayo Clin Proc 1990 Feb;65(2):164-72) MeSH
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Organization Involved with Phase 3 Indications (2)
Organization Involved with Phase 2 Indications (26)
Organization Involved with Phase 1 Indications (7)
Organization Involved with Other Experimental Indications (2)
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UMLS Data
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