Related MeSH Hierarchy (9)
Diseases [C] » Musculoskeletal Diseases [C05] » Muscular Diseases » Mitochondrial Myopathies » Mitochondrial Encephalomyopathies » MELAS Syndrome
Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Brain Diseases » Brain Diseases, Metabolic » Brain Diseases, Metabolic, Inborn » MELAS Syndrome
Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Brain Diseases » Cerebrovascular Disorders » Cerebral Small Vessel Diseases » MELAS Syndrome
Diseases [C] » Nervous System Diseases [C10] » Neuromuscular Diseases » Muscular Diseases » Mitochondrial Myopathies » Mitochondrial Encephalomyopathies » MELAS Syndrome
Diseases [C] » Cardiovascular Diseases [C14] » Vascular Diseases » Cerebrovascular Disorders » Cerebral Small Vessel Diseases » MELAS Syndrome
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Genetic Diseases, Inborn » Metabolism, Inborn Errors » Brain Diseases, Metabolic, Inborn » MELAS Syndrome
Diseases [C] » Nutritional and Metabolic Diseases [C18] » Metabolic Diseases » Brain Diseases, Metabolic » Brain Diseases, Metabolic, Inborn » MELAS Syndrome
Diseases [C] » Nutritional and Metabolic Diseases [C18] » Metabolic Diseases » Metabolism, Inborn Errors » Brain Diseases, Metabolic, Inborn » MELAS Syndrome
Diseases [C] » Nutritional and Metabolic Diseases [C18] » Metabolic Diseases » Mitochondrial Diseases » Mitochondrial Myopathies » Mitochondrial Encephalomyopathies » MELAS Syndrome
Description
A mitochondrial disorder characterized by focal or generalized seizures, episodes of transient or persistent neurologic dysfunction resembling strokes, and ragged-red fibers on muscle biopsy. Affected individuals tend to be normal at birth through early childhood, then experience growth failure, episodic vomiting, and recurrent cerebral insults resulting in visual loss and hemiparesis. The cortical lesions tend to occur in the parietal and occipital lobes and are not associated with vascular occlusion. VASCULAR HEADACHE is frequently associated and the disorder tends to be familial. (From Joynt, Clinical Neurology, 1992, Ch56, p117) MeSH
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Phase 4 Indicated Drugs (1)
Phase 2 Indicated Drugs (5)
Phase 1 Indicated Drugs (2)
Other Experimental Indicated Drugs (2)
Organization Involved with Phase 4 Indications (2)
Organization Involved with Phase 2 Indications (7)
Organization Involved with Phase 1 Indications (6)
Organization Involved with Other Experimental Indications (1)
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UMLS Data
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