Diseases [C] » Urogenital Diseases [C12] » Genital Diseases » Genital Diseases, Female » Adnexal Diseases » Ovarian Diseases » Primary Ovarian Insufficiency
Diseases [C] » Endocrine System Diseases [C19] » Gonadal Disorders » Ovarian Diseases » Primary Ovarian Insufficiency
Diseases [C] » Urogenital Diseases [C12] » Female Urogenital Diseases and Pregnancy Complications » Female Urogenital Diseases » Genital Diseases, Female » Adnexal Diseases » Ovarian Diseases » Primary Ovarian Insufficiency
Description
Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections. The most commonly known genetic cause is the expansion of a CGG repeat to 55 to 199 copies in the 5' untranslated region in the X-linked FMR1 gene. MeSH
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Approved Indicated Drugs (2)
Phase 3 Indicated Drugs (3)
Other Experimental Indicated Drugs (7)
Organization Involved with Phase 4 Indications (6)
Organization Involved with Phase 3 Indications (7)
Organization Involved with Phase 2 Indications (18)
Organization Involved with Phase 1 Indications (9)
Organization Involved with Other Experimental Indications (9)
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UMLS Data
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