Diseases [C] » Nervous System Diseases [C10] » Nervous System Malformations » Neural Tube Defects » Spinal Dysraphism
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Congenital Abnormalities » Nervous System Malformations » Neural Tube Defects » Spinal Dysraphism
Description
Congenital defects of closure of one or more vertebral arches, which may be associated with malformations of the spinal cord, nerve roots, congenital fibrous bands, lipomas, and congenital cysts. These malformations range from mild (e.g., SPINA BIFIDA OCCULTA) to severe, including rachischisis where there is complete failure of neural tube and spinal cord fusion, resulting in exposure of the spinal cord at the surface. Spinal dysraphism includes all forms of spina bifida. The open form is called SPINA BIFIDA CYSTICA and the closed form is SPINA BIFIDA OCCULTA. (From Joynt, Clinical Neurology, 1992, Ch55, p34) MeSH
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Subtype Terms (2)
Spina Bifida Occulta
1 approved drug
Phase 4 Indicated Drugs (2)
Other Experimental Indicated Drugs (4)
Organization Involved with Phase 3 Indications (2)
Organization Involved with Phase 2 Indications (3)
Organization Involved with Phase 1 Indications (2)
Organization Involved with Other Experimental Indications (10)
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