Related MeSH Hierarchy (5)
Diseases [C] » Infections [C01] » Central Nervous System Infections » Myelitis » Paraparesis, Tropical Spastic
Diseases [C] » Infections [C01] » Virus Diseases » RNA Virus Infections » Retroviridae Infections » Deltaretrovirus Infections » HTLV-I Infections » Paraparesis, Tropical Spastic
Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Central Nervous System Infections » Myelitis » Paraparesis, Tropical Spastic
Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Spinal Cord Diseases » Myelitis » Paraparesis, Tropical Spastic
Diseases [C] » Nervous System Diseases [C10] » Neuroinflammatory Diseases » Myelitis » Paraparesis, Tropical Spastic
Description
A subacute paralytic myeloneuropathy occurring endemically in tropical areas such as the Caribbean, Colombia, India, and Africa, as well as in the southwestern region of Japan; associated with infection by HUMAN T-CELL LEUKEMIA VIRUS I. Clinical manifestations include a slowly progressive spastic weakness of the legs, increased reflexes, Babinski signs, incontinence, and loss of vibratory and position sensation. On pathologic examination inflammatory, demyelination, and necrotic lesions may be found in the spinal cord. (Adams et al., Principles of Neurology, 6th ed, p1239) MeSH
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Phase 3 Indicated Drugs (4)
Phase 2 Indicated Drugs (3)
Organization Involved with Phase 3 Indications (6)
Organization Involved with Phase 2 Indications (1)
Organization Involved with Phase 1 Indications (3)
Organization Involved with Other Experimental Indications (2)
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UMLS Data
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