Diseases [C] » Cardiovascular Diseases [C14] » Heart Diseases » Arrhythmias, Cardiac » Pre-Excitation Syndromes » Wolff-Parkinson-White Syndrome
Diseases [C] » Cardiovascular Diseases [C14] » Heart Diseases » Cardiac Conduction System Disease » Pre-Excitation Syndromes » Wolff-Parkinson-White Syndrome
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Congenital Abnormalities » Cardiovascular Abnormalities » Heart Defects, Congenital » Wolff-Parkinson-White Syndrome
Description
A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulses are abnormally conducted to the HEART VENTRICLES via an ACCESSORY CONDUCTING PATHWAY that is located between the wall of the right or left atria and the ventricles, also known as a BUNDLE OF KENT. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase. MeSH
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