Related MeSH Hierarchy (7)
Diseases [C] » Pathological Conditions, Signs and Symptoms [C23] » Signs and Symptoms » Neurologic Manifestations » Paralysis » Ophthalmoplegia » Supranuclear Palsy, Progressive
Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Brain Diseases » Basal Ganglia Diseases » Supranuclear Palsy, Progressive
Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Movement Disorders » Supranuclear Palsy, Progressive
Diseases [C] » Nervous System Diseases [C10] » Cranial Nerve Diseases » Ocular Motility Disorders » Ophthalmoplegia » Supranuclear Palsy, Progressive
Diseases [C] » Nervous System Diseases [C10] » Neurodegenerative Diseases » Tauopathies » Supranuclear Palsy, Progressive
Diseases [C] » Nervous System Diseases [C10] » Neurologic Manifestations » Paralysis » Ophthalmoplegia » Supranuclear Palsy, Progressive
Diseases [C] » Eye Diseases [C11] » Ocular Motility Disorders » Ophthalmoplegia » Supranuclear Palsy, Progressive
Description
A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7) MeSH
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Phase 4 Indicated Drugs (3)
Phase 1 Indicated Drugs (9)
Other Experimental Indicated Drugs (10)
Organization Involved with Phase 4 Indications (2)
Organization Involved with Phase 3 Indications (11)
Organization Involved with Phase 2 Indications (19)
Organization Involved with Phase 1 Indications (11)
Organization Involved with Other Experimental Indications (4)
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UMLS Data
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