Related MeSH Hierarchy (4)
Diseases [C] » Nervous System Diseases [C10] » Autonomic Nervous System Diseases » Primary Dysautonomias » Multiple System Atrophy » Shy-Drager Syndrome
Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Brain Diseases » Basal Ganglia Diseases » Multiple System Atrophy » Shy-Drager Syndrome
Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Movement Disorders » Multiple System Atrophy » Shy-Drager Syndrome
Diseases [C] » Cardiovascular Diseases [C14] » Vascular Diseases » Hypotension » Shy-Drager Syndrome
Description
A progressive neurodegenerative condition of the central and autonomic nervous systems characterized by atrophy of the preganglionic lateral horn neurons of the thoracic spinal cord. This disease is generally considered a clinical variant of MULTIPLE SYSTEM ATROPHY. Affected individuals present in the fifth or sixth decade with ORTHOSTASIS and bladder dysfunction; and later develop FECAL INCONTINENCE; anhidrosis; ATAXIA; IMPOTENCE; and alterations of tone suggestive of basal ganglia dysfunction. (From Adams et al., Principles of Neurology, 6th ed, p536) MeSH
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Phase 1 Indicated Drugs (3)
Other Experimental Indicated Drugs (1)
Organization Involved with Phase 4 Indications (2)
Organization Involved with Phase 3 Indications (24)
Organization Involved with Phase 2 Indications (13)
Organization Involved with Phase 1 Indications (12)
Organization Involved with Other Experimental Indications (5)
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UMLS Data
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