Shy-Drager Syndrome D012791

Related MeSH Hierarchy (4)

Diseases [C] » Cardiovascular Diseases [C14] » Vascular Diseases » Hypotension » Shy-Drager Syndrome

Description

A progressive neurodegenerative condition of the central and autonomic nervous systems characterized by atrophy of the preganglionic lateral horn neurons of the thoracic spinal cord. This disease is generally considered a clinical variant of MULTIPLE SYSTEM ATROPHY. Affected individuals present in the fifth or sixth decade with ORTHOSTASIS and bladder dysfunction; and later develop FECAL INCONTINENCE; anhidrosis; ATAXIA; IMPOTENCE; and alterations of tone suggestive of basal ganglia dysfunction. (From Adams et al., Principles of Neurology, 6th ed, p536)   MeSH

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Other Experimental Indicated Drugs (1)


Organization Involved with Phase 4 Indications (2)

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