Diseases [C] » Infections [C01] » Virus Diseases » DNA Virus Infections » Herpesviridae Infections » Sarcoma, Kaposi
Diseases [C] » Neoplasms [C04] » Neoplasms by Histologic Type » Neoplasms, Connective and Soft Tissue » Sarcoma » Sarcoma, Kaposi
Diseases [C] » Neoplasms [C04] » Neoplasms by Histologic Type » Neoplasms, Vascular Tissue » Sarcoma, Kaposi
Description
A multicentric, malignant neoplastic vascular proliferation characterized by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal areas. The tumors have endothelium-lined channels and vascular spaces admixed with variably sized aggregates of spindle-shaped cells, and often remain confined to the skin and subcutaneous tissue, but widespread visceral involvement may occur. Kaposi's sarcoma occurs spontaneously in Jewish and Italian males in Europe and the United States. An aggressive variant in young children is endemic in some areas of Africa. A third form occurs in about 0.04% of kidney transplant patients. There is also a high incidence in AIDS patients. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, pp2105-7) HHV-8 is the suspected cause. MeSH
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Approved Indicated Drugs (3)
Phase 3 Indicated Drugs (7)
Phase 2 Indicated Drugs (34)
Other Experimental Indicated Drugs (2)
Organization Involved with Phase 4 Indications (14)
Organization Involved with Phase 3 Indications (15)
Organization Involved with Phase 2 Indications (49)
AIDS and Cancer Specimen Resource
Apogee Biotechnology Corporation
Assistance Publique - Hôpitaux de Paris
Hoosier Cancer Research Network
Institut National de la Santé Et de la Recherche Médicale, France
Organization Involved with Phase 1 Indications (11)
Organization Involved with Other Experimental Indications (3)
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UMLS Data
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