Related MeSH Hierarchy (7)
Diseases [C] » Neoplasms [C04] » Neoplasms by Site » Eye Neoplasms » Retinal Neoplasms » Retinoblastoma
Diseases [C] » Neoplasms [C04] » Neoplasms by Histologic Type » Neoplasms, Glandular and Epithelial » Neoplasms, Neuroepithelial » Retinoblastoma
Diseases [C] » Eye Diseases [C11] » Eye Diseases, Hereditary » Retinoblastoma
Diseases [C] » Neoplasms [C04] » Neoplasms by Histologic Type » Neoplasms, Germ Cell and Embryonal » Neuroectodermal Tumors » Neoplasms, Neuroepithelial » Retinoblastoma
Diseases [C] » Neoplasms [C04] » Neoplasms by Histologic Type » Neoplasms, Nerve Tissue » Neuroectodermal Tumors » Neoplasms, Neuroepithelial » Retinoblastoma
Diseases [C] » Eye Diseases [C11] » Eye Neoplasms » Retinal Neoplasms » Retinoblastoma
Diseases [C] » Eye Diseases [C11] » Retinal Diseases » Retinal Neoplasms » Retinoblastoma
Description
A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104) MeSH
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Approved Indicated Drugs (1)
Phase 4 Indicated Drugs (5)
Phase 1 Indicated Drugs (18)
Other Experimental Indicated Drugs (5)
Organization Involved with Phase 4 Indications (12)
Organization Involved with Phase 3 Indications (11)
Organization Involved with Phase 2 Indications (39)
Organization Involved with Phase 1 Indications (10)
Organization Involved with Other Experimental Indications (10)
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UMLS Data
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