Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Hydrolases » Peptide Hydrolases » Aspartic Acid Proteases » Aspartic Acid Endopeptidases » Renin
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Hydrolases » Peptide Hydrolases » Endopeptidases » Aspartic Acid Endopeptidases » Renin
Chemicals and Drugs [D] » Enzymes and Coenzymes [D08] » Enzymes » Hydrolases » Peptide Hydrolases » Proprotein Convertases » Renin
Description
A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19. MeSH
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Phase 3 Indicated Drugs (1)
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