Related MeSH Hierarchy (6)
Phenomena and Processes [G] » Genetic Phenomena [G05] » Genetic Structures » Chromosomes » Chromosomes, Mammalian » Chromosomes, Human » Chromosomes, Human, 6-12 and X » Chromosomes, Human, Pair 9 » Philadelphia Chromosome
Anatomy [A] » Cells [A11] » Cellular Structures » Chromosomes » Chromosomes, Mammalian » Chromosomes, Human » Chromosomes, Human, 6-12 and X » Chromosomes, Human, Pair 9 » Philadelphia Chromosome
Anatomy [A] » Cells [A11] » Cellular Structures » Chromosomes » Chromosomes, Mammalian » Chromosomes, Human » Chromosomes, Human, 21-22 and Y » Chromosomes, Human, Pair 22 » Philadelphia Chromosome
Diseases [C] » Pathological Conditions, Signs and Symptoms [C23] » Pathologic Processes » Chromosome Aberrations » Translocation, Genetic » Philadelphia Chromosome
Phenomena and Processes [G] » Genetic Phenomena [G05] » Genetic Structures » Chromosomes » Chromosomes, Mammalian » Chromosomes, Human » Chromosomes, Human, 21-22 and Y » Chromosomes, Human, Pair 22 » Philadelphia Chromosome
Phenomena and Processes [G] » Genetic Phenomena [G05] » Genetic Variation » Mutation » Chromosome Aberrations » Translocation, Genetic » Philadelphia Chromosome
Description
An aberrant form of human CHROMOSOME 22 characterized by translocation of the distal end of chromosome 9 from 9q34, to the long arm of chromosome 22 at 22q11. It is present in the bone marrow cells of 80 to 90 per cent of patients with chronic myelocytic leukemia (LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE). MeSH
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Approved Indicated Drugs (1)
Phase 3 Indicated Drugs (2)
Phase 2 Indicated Drugs (6)
Organization Involved with Phase 4 Indications (7)
Organization Involved with Phase 3 Indications (11)
Organization Involved with Phase 2 Indications (37)
Azienda Ospedaliera San Gerardo di Monza
Cancer and Leukemia Group B (CALGB)
Gruppo Italiano Malattie EMatologiche dell'Adulto
Hospital Santa Marcelina, Sao Paulo, Brasil
Organization Involved with Phase 1 Indications (13)
Organization Involved with Other Experimental Indications (1)
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