Related MeSH Hierarchy (4)
Diseases [C] » Musculoskeletal Diseases [C05] » Muscular Diseases » Paralyses, Familial Periodic
Diseases [C] » Nervous System Diseases [C10] » Neuromuscular Diseases » Muscular Diseases » Paralyses, Familial Periodic
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Genetic Diseases, Inborn » Metabolism, Inborn Errors » Metal Metabolism, Inborn Errors » Paralyses, Familial Periodic
Diseases [C] » Nutritional and Metabolic Diseases [C18] » Metabolic Diseases » Metabolism, Inborn Errors » Metal Metabolism, Inborn Errors » Paralyses, Familial Periodic
Description
A heterogenous group of inherited disorders characterized by recurring attacks of rapidly progressive flaccid paralysis or myotonia. These conditions have in common a mutation of the gene encoding the alpha subunit of the sodium channel in skeletal muscle. They are frequently associated with fluctuations in serum potassium levels. Periodic paralysis may also occur as a non-familial process secondary to THYROTOXICOSIS and other conditions. (From Adams et al., Principles of Neurology, 6th ed, p1481) MeSH
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Subtype Terms (2)
Hypokalemic Periodic Paralysis
2 approved drugs
Paralysis, Hyperkalemic Periodic
2 approved drugs
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UMLS Data
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