Related MeSH Hierarchy (5)
Diseases [C] » Nervous System Diseases [C10] » Neuroinflammatory Diseases » Meningitis » Meningitis, Bacterial » Meningitis, Meningococcal
Diseases [C] » Infections [C01] » Bacterial Infections and Mycoses » Bacterial Infections » Central Nervous System Bacterial Infections » Meningitis, Bacterial » Meningitis, Meningococcal
Diseases [C] » Infections [C01] » Bacterial Infections and Mycoses » Bacterial Infections » Gram-Negative Bacterial Infections » Neisseriaceae Infections » Meningococcal Infections » Meningitis, Meningococcal
Diseases [C] » Infections [C01] » Central Nervous System Infections » Central Nervous System Bacterial Infections » Meningitis, Bacterial » Meningitis, Meningococcal
Diseases [C] » Nervous System Diseases [C10] » Central Nervous System Diseases » Central Nervous System Infections » Central Nervous System Bacterial Infections » Meningitis, Bacterial » Meningitis, Meningococcal
Description
A fulminant infection of the meninges and subarachnoid fluid by the bacterium NEISSERIA MENINGITIDIS, producing diffuse inflammation and peri-meningeal venous thromboses. Clinical manifestations include FEVER, nuchal rigidity, SEIZURES, severe HEADACHE, petechial rash, stupor, focal neurologic deficits, HYDROCEPHALUS, and COMA. The organism is usually transmitted via nasopharyngeal secretions and is a leading cause of meningitis in children and young adults. Organisms from Neisseria meningitidis serogroups A, B, C, Y, and W-135 have been reported to cause meningitis. (From Adams et al., Principles of Neurology, 6th ed, pp689-701; Curr Opin Pediatr 1998 Feb;10(1):13-8) MeSH
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Subtype Terms (1)
Approved Indicated Drugs (12)
meningococcal conjugate vaccine - Menactra (Menactra)
Meningococcal (Groups A, C, Y, W) Conjugate Vaccine (MenQuadfi)
Phase 3 Indicated Drugs (18)
acellular pertussis vaccine (including diptheria and tetanus toxoids) (Tripedia)
DTaP, inactivated poliovirus, haemophilus influenzae b conjugate, hepatitis b vaccine (Pediarix)
hepatitis-a virus (inactivated) / hepatitis-b surface antigen (twinrix)
hepatitis b vaccine (recombinant) (Recombivax)
inactivated japanese encephalitis vaccine (Ixiaro)
Phase 2 Indicated Drugs (2)
Other Experimental Indicated Drugs (1)
Organization Involved with Phase 4 Indications (12)
Organization Involved with Phase 3 Indications (9)
Organization Involved with Phase 2 Indications (10)
Organization Involved with Phase 1 Indications (2)
Organization Involved with Other Experimental Indications (1)
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UMLS Data
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