Related MeSH Hierarchy (4)
Diseases [C] » Nutritional and Metabolic Diseases [C18] » Metabolic Diseases » Metabolism, Inborn Errors » Carbohydrate Metabolism, Inborn Errors » Mannosidase Deficiency Diseases » alpha-Mannosidosis
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Genetic Diseases, Inborn » Metabolism, Inborn Errors » Carbohydrate Metabolism, Inborn Errors » Mannosidase Deficiency Diseases » alpha-Mannosidosis
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Genetic Diseases, Inborn » Metabolism, Inborn Errors » Lysosomal Storage Diseases » Mannosidase Deficiency Diseases » alpha-Mannosidosis
Diseases [C] » Nutritional and Metabolic Diseases [C18] » Metabolic Diseases » Metabolism, Inborn Errors » Lysosomal Storage Diseases » Mannosidase Deficiency Diseases » alpha-Mannosidosis
Description
An inborn error of metabolism marked by a defect in the lysosomal isoform of ALPHA-MANNOSIDASE activity that results in lysosomal accumulation of mannose-rich intermediate metabolites. Virtually all patients have psychomotor retardation, facial coarsening, and some degree of dysostosis multiplex. It is thought to be an autosomal recessive disorder. MeSH
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Approved Indicated Drugs (1)
Phase 1 Indicated Drugs (1)
Organization Involved with Phase 3 Indications (5)
Organization Involved with Phase 2 Indications (4)
Organization Involved with Phase 1 Indications (1)
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