Lichen Planus D008010

Description

An inflammatory, pruritic disease of the skin and mucous membranes, which can be either generalized or localized. It is characterized by distinctive purplish, flat-topped papules having a predilection for the trunk and flexor surfaces. The lesions may be discrete or coalesce to form plaques. Histologically, there is a "saw-tooth" pattern of epidermal hyperplasia and vacuolar alteration of the basal layer of the epidermis along with an intense upper dermal inflammatory infiltrate composed predominantly of T-cells. Etiology is unknown.   MeSH

Subtype Terms (1)

Lichen Planus, Oral
47 drugs (20 approved, 27 experimental)


Phase 4 Indicated Drugs (1)

Phase 1 Indicated Drugs (2)


Organization Involved with Phase 1 Indications (1)

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UMLS Data


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