Diseases [C] » Skin and Connective Tissue Diseases [C17] » Skin Diseases » Skin Diseases, Papulosquamous » Lichenoid Eruptions » Lichen Planus
Description
An inflammatory, pruritic disease of the skin and mucous membranes, which can be either generalized or localized. It is characterized by distinctive purplish, flat-topped papules having a predilection for the trunk and flexor surfaces. The lesions may be discrete or coalesce to form plaques. Histologically, there is a "saw-tooth" pattern of epidermal hyperplasia and vacuolar alteration of the basal layer of the epidermis along with an intense upper dermal inflammatory infiltrate composed predominantly of T-cells. Etiology is unknown. MeSH
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Subtype Terms (1)
Lichen Planus, Oral
56 drugs (25 approved, 31 experimental)
Approved Indicated Drugs (1)
Phase 4 Indicated Drugs (1)
Phase 2 Indicated Drugs (15)
Phase 1 Indicated Drugs (1)
Other Experimental Indicated Drugs (7)
Organization Involved with Phase 4 Indications (6)
Organization Involved with Phase 3 Indications (11)
Organization Involved with Phase 2 Indications (43)
Case Western Reserve University
College of Dental Sciences, Davangere
College of Dental Sciences, India
Icahn School of Medicine at Mount Sinai
Mashhad University of Medical Sciences
National Institute of Dental and Craniofacial Research (NIDCR)
National Institutes of Health (NIH)
Oregon Health and Science University
Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Organization Involved with Phase 1 Indications (1)
Organization Involved with Other Experimental Indications (10)
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UMLS Data
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