Related MeSH Hierarchy (10)
Diseases [C] » Pathological Conditions, Signs and Symptoms [C23] » Pathologic Processes » Disease Attributes » Chronic Disease » Ophthalmoplegia, Chronic Progressive External » Kearns-Sayre Syndrome
Diseases [C] » Nervous System Diseases [C10] » Neurologic Manifestations » Paralysis » Ophthalmoplegia » Ophthalmoplegia, Chronic Progressive External » Kearns-Sayre Syndrome
Diseases [C] » Musculoskeletal Diseases [C05] » Muscular Diseases » Mitochondrial Myopathies » Ophthalmoplegia, Chronic Progressive External » Kearns-Sayre Syndrome
Diseases [C] » Nervous System Diseases [C10] » Cranial Nerve Diseases » Ocular Motility Disorders » Ophthalmoplegia » Ophthalmoplegia, Chronic Progressive External » Kearns-Sayre Syndrome
Diseases [C] » Nervous System Diseases [C10] » Neuromuscular Diseases » Muscular Diseases » Mitochondrial Myopathies » Ophthalmoplegia, Chronic Progressive External » Kearns-Sayre Syndrome
Diseases [C] » Eye Diseases [C11] » Ocular Motility Disorders » Ophthalmoplegia » Ophthalmoplegia, Chronic Progressive External » Kearns-Sayre Syndrome
Diseases [C] » Eye Diseases [C11] » Retinal Diseases » Retinal Degeneration » Retinal Dystrophies » Retinitis Pigmentosa » Kearns-Sayre Syndrome
Diseases [C] » Cardiovascular Diseases [C14] » Heart Diseases » Cardiomyopathies » Kearns-Sayre Syndrome
Diseases [C] » Nutritional and Metabolic Diseases [C18] » Metabolic Diseases » Mitochondrial Diseases » Mitochondrial Myopathies » Ophthalmoplegia, Chronic Progressive External » Kearns-Sayre Syndrome
Diseases [C] » Pathological Conditions, Signs and Symptoms [C23] » Signs and Symptoms » Neurologic Manifestations » Paralysis » Ophthalmoplegia » Ophthalmoplegia, Chronic Progressive External » Kearns-Sayre Syndrome
Description
A mitochondrial disorder featuring the triad of chronic progressive EXTERNAL OPHTHALMOPLEGIA, cardiomyopathy (CARDIOMYOPATHIES) with conduction block (HEART BLOCK), and RETINITIS PIGMENTOSA. Disease onset is in the first or second decade. Elevated CSF protein, sensorineural deafness, seizures, and pyramidal signs may also be present. Ragged-red fibers are found on muscle biopsy. (Adams et al., Principles of Neurology, 6th ed, p984) MeSH
Hierarchy View
Hierarchy Tree View
UMLS Data
YOU AGREE THAT THE INFORMATION PROVIDED ON THIS WEBSITE IS PROVIDED “AS IS”, WITHOUT ANY WARRANTY OF ANY KIND, EXPRESSED OR IMPLIED, INCLUDING WITHOUT LIMITATION WARRANTIES OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PURPOSE, OR NON-INFRINGEMENT OF ANY THIRD-PARTY PATENT, COPYRIGHT, OR ANY OTHER THIRD-PARTY RIGHT. IN NO EVENT SHALL THE CREATORS OF THE WEBSITE OR WASHINGTON UNIVERSITY BE LIABLE FOR ANY DIRECT, INDIRECT, SPECIAL, OR CONSEQUENTIAL DAMAGES ARISING OUT OF OR IN ANY WAY CONNECTED WITH THE WEBSITE, THE USE OF THE WEBSITE, OR THIS AGREEMENT, WHETHER IN BREACH OF CONTRACT, TORT OR OTHERWISE, EVEN IF SUCH PARTY IS ADVISED OF THE POSSIBILITY OF SUCH DAMAGES.
