Related MeSH Hierarchy (4)
Diseases [C] » Nutritional and Metabolic Diseases [C18] » Metabolic Diseases » Lipid Metabolism Disorders » Lipid Metabolism, Inborn Errors » Hyperlipoproteinemia Type III
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Genetic Diseases, Inborn » Metabolism, Inborn Errors » Lipid Metabolism, Inborn Errors » Hyperlipoproteinemia Type III
Diseases [C] » Nutritional and Metabolic Diseases [C18] » Metabolic Diseases » Lipid Metabolism Disorders » Dyslipidemias » Hyperlipidemias » Hyperlipoproteinemias » Hyperlipoproteinemia Type III
Diseases [C] » Nutritional and Metabolic Diseases [C18] » Metabolic Diseases » Metabolism, Inborn Errors » Lipid Metabolism, Inborn Errors » Hyperlipoproteinemia Type III
Description
An autosomal recessively inherited disorder characterized by the accumulation of intermediate-density lipoprotein (IDL or broad-beta-lipoprotein). IDL has a CHOLESTEROL to TRIGLYCERIDES ratio greater than that of VERY-LOW-DENSITY LIPOPROTEINS. This disorder is due to mutation of APOLIPOPROTEINS E, a receptor-binding component of VLDL and CHYLOMICRONS, resulting in their reduced clearance and high plasma levels of both cholesterol and triglycerides. MeSH
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Approved Indicated Drugs (2)
Phase 4 Indicated Drugs (1)
Phase 3 Indicated Drugs (3)
Organization Involved with Phase 4 Indications (4)
Organization Involved with Phase 3 Indications (1)
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UMLS Data
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