Related MeSH Hierarchy (4)
Diseases [C] » Neoplasms [C04] » Neoplasms, Multiple Primary » Hamartoma Syndrome, Multiple
Diseases [C] » Neoplasms [C04] » Neoplastic Syndromes, Hereditary » Hamartoma Syndrome, Multiple
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Genetic Diseases, Inborn » Neoplastic Syndromes, Hereditary » Hamartoma Syndrome, Multiple
Description
A hereditary disease characterized by multiple ectodermal, mesodermal, and endodermal nevoid and neoplastic anomalies. Facial trichilemmomas and papillomatous papules of the oral mucosa are the most characteristic lesions. Individuals with this syndrome have a high risk of BREAST CANCER; THYROID CANCER; and ENDOMETRIAL CANCER. This syndrome is associated with mutations in the gene for PTEN PHOSPHATASE. MeSH
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Subtype Terms (1)
Proteus Syndrome
4 drugs (1 approved, 3 experimental)
Phase 2 Indicated Drugs (2)
Phase 1 Indicated Drugs (1)
Other Experimental Indicated Drugs (1)
Organization Involved with Phase 2 Indications (8)
Organization Involved with Other Experimental Indications (1)
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UMLS Data
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