Related MeSH Hierarchy (6)
Diseases [C] » Nervous System Diseases [C10] » Autonomic Nervous System Diseases » Primary Dysautonomias » Dysautonomia, Familial
Diseases [C] » Nervous System Diseases [C10] » Nervous System Malformations » Hereditary Sensory and Autonomic Neuropathies » Dysautonomia, Familial
Diseases [C] » Nervous System Diseases [C10] » Neurodegenerative Diseases » Heredodegenerative Disorders, Nervous System » Hereditary Sensory and Autonomic Neuropathies » Dysautonomia, Familial
Diseases [C] » Nervous System Diseases [C10] » Neuromuscular Diseases » Peripheral Nervous System Diseases » Polyneuropathies » Hereditary Sensory and Autonomic Neuropathies » Dysautonomia, Familial
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Congenital Abnormalities » Nervous System Malformations » Hereditary Sensory and Autonomic Neuropathies » Dysautonomia, Familial
Diseases [C] » Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] » Genetic Diseases, Inborn » Heredodegenerative Disorders, Nervous System » Hereditary Sensory and Autonomic Neuropathies » Dysautonomia, Familial
Description
An autosomal disorder of the peripheral and autonomic nervous systems limited to individuals of Ashkenazic Jewish descent. Clinical manifestations are present at birth and include diminished lacrimation, defective thermoregulation, orthostatic hypotension (HYPOTENSION, ORTHOSTATIC), fixed pupils, excessive SWEATING, loss of pain and temperature sensation, and absent reflexes. Pathologic features include reduced numbers of small diameter peripheral nerve fibers and autonomic ganglion neurons. (From Adams et al., Principles of Neurology, 6th ed, p1348; Nat Genet 1993;4(2):160-4) MeSH
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Phase 3 Indicated Drugs (3)
Phase 2 Indicated Drugs (4)
Organization Involved with Phase 3 Indications (1)
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UMLS Data
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