Collagen Diseases D003095

Diseases [C] » Skin and Connective Tissue Diseases [C17] » Connective Tissue Diseases » Collagen Diseases

Description

Historically, a heterogeneous group of acute and chronic diseases, including rheumatoid arthritis, systemic lupus erythematosus, progressive systemic sclerosis, dermatomyositis, etc. This classification was based on the notion that "collagen" was equivalent to "connective tissue", but with the present recognition of the different types of collagen and the aggregates derived from them as distinct entities, the term "collagen diseases" now pertains exclusively to those inherited conditions in which the primary defect is at the gene level and affects collagen biosynthesis, post-translational modification, or extracellular processing directly. (From Cecil Textbook of Medicine, 19th ed, p1494)   MeSH

Hierarchy View

Subtype Terms (6)

Ehlers-Danlos Syndrome
6 drugs (5 approved, 1 experimental)

Epidermolysis Bullosa Dystrophica
16 drugs (2 approved, 14 experimental)

Keloid
30 drugs (15 approved, 15 experimental)

Necrobiotic Disorders
 

Nephritis, Hereditary
11 drugs (7 approved, 4 experimental)

Osteogenesis Imperfecta
22 drugs (15 approved, 7 experimental)


Approved Indicated Drugs (1)


Organization Involved with Other Experimental Indications (4)

Hierarchy Tree View

UMLS Data


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