Diseases [C] » Skin and Connective Tissue Diseases [C17] » Connective Tissue Diseases » Collagen Diseases
Description
Historically, a heterogeneous group of acute and chronic diseases, including rheumatoid arthritis, systemic lupus erythematosus, progressive systemic sclerosis, dermatomyositis, etc. This classification was based on the notion that "collagen" was equivalent to "connective tissue", but with the present recognition of the different types of collagen and the aggregates derived from them as distinct entities, the term "collagen diseases" now pertains exclusively to those inherited conditions in which the primary defect is at the gene level and affects collagen biosynthesis, post-translational modification, or extracellular processing directly. (From Cecil Textbook of Medicine, 19th ed, p1494) MeSH
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Subtype Terms (6)
Ehlers-Danlos Syndrome
10 drugs (7 approved, 3 experimental)
Epidermolysis Bullosa Dystrophica
18 drugs (4 approved, 14 experimental)
Keloid
35 drugs (19 approved, 16 experimental)
Nephritis, Hereditary
14 drugs (9 approved, 5 experimental)
Osteogenesis Imperfecta
25 drugs (16 approved, 9 experimental)
Approved Indicated Drugs (2)
Organization Involved with Phase 4 Indications (10)
Organization Involved with Phase 3 Indications (11)
Organization Involved with Phase 2 Indications (8)
Organization Involved with Phase 1 Indications (5)
Organization Involved with Other Experimental Indications (4)
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UMLS Data
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